Clinical Inquiries
Clinical Inquiries
Do antipyretics prolong febrile illness?
EVIDENCE-BASED ANSWER: Antipyretics appear to have minor and variable effects on the course of febrile illness. Aspirin and acetaminophen do not...
Clinical Inquiries
Is folate supplementation indicated for patients with CAD?
EVIDENCE-BASED ANSWER: There is insufficient evidence to advocate the routine use of folate supplementation for the treatment of coronary artery...
Clinical Inquiries
Are liver function tests required for patients taking isoniazid for latent TB?
EVIDENCE-BASED ANSWER: Routine liver function test monitoring is not required for all patients on isoniazid therapy for latent tuberculosis (TB)...
Clinical Inquiries
Do ACE inhibitors prevent nephropathy in type 2 diabetes without proteinuria?
EVIDENCE-BASED ANSWER: Angiotensin-converting enzyme (ACE) inhibitors make a significant difference for patients with diabetes as a whole. If...
Clinical Inquiries
How accurate is stress radionuclide imaging for diagnosis of CAD?
EVIDENCE-BASED ANSWER: Stress radionuclide testing is a moderately accurate test compared with coronary angiography for the diagnosis of coronary...
Clinical Inquiries
Should we screen for ovarian cancer?
EVIDENCE-BASED ANSWER: Ovarian cancer screening using pelvic examination, CA-125 serum tumor marker, transvaginal ultrasound (TVU), or any...
Clinical Inquiries
What is the best way to manage benign paroxysmal positional vertigo?
EVIDENCE-BASED ANSWER: A simple repositioning maneuver, such as the Epley maneuver (Figures 1 and 2 ), performed by an experienced clinician, can...
Clinical Inquiries
Do statins cause myopathy?
EVIDENCE-BASED ANSWER: If statins (HMG-CoA reductase inhibitors) cause myopathy, the risk is very low (strength of recommendation [SOR]: A). There...
Clinical Inquiries
What is the best hypnotic for use in the elderly?
EVIDENCE-BASED ANSWER: Short-acting hypnotics such as zolpidem (Ambien) or zaleplon (Sonata) are the preferred hypnotics in the elderly because of...
Clinical Inquiries
Do systemic corticosteroids lessen symptoms in acute exacerbations of COPD?
EVIDENCE-BASED ANSWER: Systemic corticosteroids improve measures of dyspnea in patients with acute exacerbations of chronic obstructive pulmonary...
Clinical Inquiries
Does a high-fiber diet prevent colon cancer in at-risk patients?
EVIDENCE-BASED ANSWER: There is no direct evidence of an effect of dietary fiber on colon cancer incidence. A diet high in fiber has not been...