Clinical Inquiries
Clinical Inquiries
What is the best way to treat patients with white-coat hypertension?
EVIDENCE-BASED ANSWER: Evidence is conflicting regarding the risk of cardiovascular complications from white-coat hypertension. Some but not all...
Clinical Inquiries
Does a short symptom checklist accurately diagnose ADHD?
EVIDENCE-BASED ANSWER: Several abbreviated checklists perform well in distinguishing children with attention deficit/hyperactivity disorder (ADHD...
Clinical Inquiries
Should home apnea monitoring be recommended to prevent SIDS?
EVIDENCE-BASED ANSWER: While home apnea monitoring may find an increased incidence of apnea and bradycardia in preterm infants compared with term...
Clinical Inquiries
Should we discontinue Pap smear screening in women aged >65 years?
EVIDENCE-BASED ANSWER: Women with a history of regular, normal Pap smear screening should discontinue screening by age 65 years (strength of...
Clinical Inquiries
Is the ThinPrep better than conventional Pap smear at detecting cervical cancer?
EVIDENCE-BASED ANSWER: Conclusions regarding the ThinPrep are difficult to make due to the complexity of cervical cancer screening and the lack of...
Clinical Inquiries
Does treatment of acne with Retin A and tetracycline cause adverse effects?
EVIDENCE-BASED ANSWER: Adverse reactions to long-term tetracycline therapy are rare, and most will occur within 2 months of initiating therapy (...
Clinical Inquiries
Is exercise treadmill testing useful for detecting heart disease in women?
EVIDENCE-BASED ANSWER: Exercise treadmill testing has a sensitivity of 70% and specificity of 61% for the detection of coronary artery disease (...
Clinical Inquiries
How effective are leukotriene inhibitors for asthma in children?
EVIDENCE-BASED ANSWER: Evidence on the use of leukotriene inhibitors in children is insufficient to permit conclusions regarding efficacy. Given...
Clinical Inquiries
Which blood tests are most helpful in evaluating pelvic inflammatory disease?
EVIDENCE-BASED ANSWER: No individual or combination of blood tests can reliably diagnose pelvic inflammatory disease (PID) (strength of...
Clinical Inquiries
When should patients with mitral valve prolapse get endocarditis prophylaxis?
EVIDENCE-BASED ANSWER: Patients with suspected mitral valve prolapse (MVP) ( Figure 1 ) should undergo echocardiography before any procedure that...
Clinical Inquiries
What is the best macrolide for atypical pneumonia?
EVIDENCE-BASED ANSWER: Erythromycin, clarithromycin, and azithromycin are equally effective in treating pneumonia caused by Mycoplasma pneumoniae...