Clinical Inquiries
Clinical Inquiries
First- or second-generation antihistamines: which are more effective at controlling pruritus?
EVIDENCE-BASED ANSWER: For urticarial itch, first- and second-generation antihistamines have similar clinical benefit and are superior to placebo...
Clinical Inquiries
What is the most effective way for relieving constipation in children aged >1 year?
EVIDENCE-BASED ANSWER: A combination of laxatives, behavioral therapy, and balanced diet is the treatment of choice for pediatric constipation (...
Clinical Inquiries
What is the best approach for managing recurrent bacterial vaginosis?
EVIDENCE-BASED ANSWER: The best way to prevent recurrent bacterial vaginosis is to treat the initial episode with the most effective regimen....
Clinical Inquiries
Should we screen women for hypothyroidism?
EVIDENCE-BASED ANSWER: Though evidence is insufficient to recommend screening all women for hypothyroidism, women aged >50 years are at...
Clinical Inquiries
When should patients with stroke receive thrombolytics?
EVIDENCE-BASED ANSWER: Thrombolytic therapy should be limited to patients with acute ischemic stroke who meet strict inclusion and exclusion...
Clinical Inquiries
Is methylphenidate useful for treating adolescents with ADHD?
EVIDENCE-BASED ANSWER: Methylphenidate (Ritalin) is effective in the short-term treatment of attention deficit/hyperactivity disorder (ADHD) (...
Clinical Inquiries
Does yoga speed healing for patients with low back pain?
EVIDENCE-BASED ANSWER: The use of yoga is consistent with recommendations for activity, as tolerated, for patients with low back pain. Literature...
Clinical Inquiries
Do inhaled beta-agonists control cough in URIs or acute bronchitis?
EVIDENCE-BASED ANSWER: Patients who receive inhaled beta-agonists for cough due to acute upper respiratory infections (URI) are just as likely to...
Clinical Inquiries
Is an outpatient workup safe for patients with a transient ischemic attack?
EVIDENCE-BASED ANSWER: There is no compelling evidence that outpatient diagnostic workup of patients with transient ischemic attack (TIA) is less...
Clinical Inquiries
Does combining aspirin and warfarin decrease the risk of stroke for patients with nonvalvular atrial fibrillation?
EVIDENCE-BASED ANSWER: Adjusted-dose warfarin (international normalized ratio [INR]=2.0–3.0) remains the most efficacious antithrombotic regimen...
Clinical Inquiries
Do statins reduce the risk of stroke?
EVIDENCE-BASED ANSWER: HMG Co-A reductase inhibitors (statins) are effective for primary prevention of ischemic stroke in people who have a...