News
Blood group O linked to decreased risk of SARS-CoV-2 infection
- Author:
- Mark S. Lesney, PhD
A retrospective analysis of all Danish individuals with a known ABO blood group tested for SARS-CoV-2 showed a lower infection risk for SARS-CoV-2...
News
Study: Complications from childhood ALL and its treatment are common, but can be managed
- Author:
- Mark S. Lesney, PhD
Despite survival after treatment of acute lymphoblastic leukemia, a high percentage of children suffered acute...
News
Older adults with multiple myeloma face heavy burden of care
- Author:
- Mark S. Lesney, PhD
Newly diagnosed older adults with multiple myeloma (MM) face a heavy burden of treatment.
Article
Meta-analysis: Acalabrutinib showed better PFS and OS than other frontline CLL therapies
- Author:
- Mark S. Lesney, PhD
Progression-free and overall survival improved with acalabrutinib over other chronic lymphocytic leukemia...
News
Orthopedic problems in children can be the first indication of acute lymphoblastic leukemia
- Author:
- Mark S. Lesney, PhD
The diagnosis of acute lymphoblastic leukemia (ALL) is often delayed because of vague presentation and normal...
News
Initial response to novel agents preps MM patients for favorable transplant outcomes
- Author:
- Mark S. Lesney, PhD
Triplet induction outperformed doublet in early outcomes, but later outcome differences were not statistically significant.
News
Two new protein biomarkers may serve as prognostic indicators for outcomes in CLL
- Author:
- Mark S. Lesney, PhD
Study also validated the prognostic value of two previously studied biomarkers.
News
Low VWF levels or blood group O not linked to intracerebral hemorrhage risk
- Author:
- Mark S. Lesney, PhD
Unlike some previous studies, low levels of von Willebrand Factor (VWF) and blood group O were not associated...
News
Statins linked to improved survival in multiple myeloma
- Author:
- Mark S. Lesney, PhD
Statin use was associated with an overall reduction of the risk of death in MM patients, including those treated...
News
Oxidative stress linked to cytogenetic abnormalities in CLL
- Author:
- Mark S. Lesney, PhD
Patients with B-cell chronic lymphocytic leukemia had increased serum oxidative stress markers and an imbalance...
News
CSF metabolomic profile linked to cancer-related fatigue in children with ALL
- Author:
- Mark S. Lesney, PhD
Cerebrospinal fluid revealed three metabolites significantly associated with cancer-related fatigue in children...
Opinion
Chronicles of Cancer: A history of mammography, part 2
- Author:
- Mark S. Lesney, PhD
The history of mammography is rife with controversy, enmeshed in the War on Cancer, corporate and professional interests, and the women’s rights...
News
Napabucasin suppressed tumor growth in DLBCL cell lines
- Author:
- Mark S. Lesney, PhD
Napabucasin suppressed tumor growth, decreased Ki67 and CD31 and increased cleaved caspase-3.
News
Age, other risk factors predict length of MM survival
- Author:
- Mark S. Lesney, PhD
Autologous stem cell treatment was more effective in those who developed MM at a younger age.
News
Antihistamines synergistically induce CLL cell death with TK inhibitors
- Author:
- Mark S. Lesney, PhD
Over-the-counter antihistamines induced synergistic cytotoxicity with TK inhibitors.