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    • Deprecated function: Return type of DatabaseStatementBase::execute($args = [], $options = []) should either be compatible with PDOStatement::execute(?array $params = null): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2246 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::current() should either be compatible with Iterator::current(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::next() should either be compatible with Iterator::next(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::key() should either be compatible with Iterator::key(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::valid() should either be compatible with Iterator::valid(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::rewind() should either be compatible with Iterator::rewind(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).

    Mark S. Lesney, PhD

    News

    Sepsis transition program may lower mortality in patients discharged to post-acute care

    Author:
    Mark S. Lesney, PhD
    Publish date: October 17, 2022

    Sepsis survivors discharged to post-acute care facilities are at high risk.

    • Read More

    News

    New ILD, asthma, and COPD trials

    Author:
    Mark S. Lesney, PhD
    Publish date: August 9, 2022

    Three new and still-recruiting trials of interest to pulmonologists and their patients are presented in this debut presentation of Clinical Trials...

    • Read More

    News

    Sleep, not smoke, the key to COPD exacerbations?

    Author:
    Mark S. Lesney, PhD
    Publish date: June 15, 2022

    Individuals who self-reported having poor-quality sleep had a 25%-95% higher risk of COPD exacerbations.

    • Read More

    News

    NIAID trial to test asthma drug in disadvantaged urban children

    Author:
    Mark S. Lesney, PhD
    Publish date: June 3, 2022

    “We need to find out how well approved asthma drugs work for disadvantaged children of color living in urban areas.”

    • Read More

    News

    COPD screening for asymptomatic adults? USPSTF weighs in, again

    Author:
    Mark S. Lesney, PhD
    Publish date: May 10, 2022

    To update its 2016 recommendation, the U.S. Preventive Services Task Force commissioned a reaffirmation evidence...

    • Read More

    News

    FDA approves generic Symbicort for asthma, COPD

    Author:
    Mark S. Lesney, PhD
    Publish date: March 16, 2022

    The approval was given for a metered-dose inhaler that contains both budesonide and formoterol.

    • Read More

    News

    FDA approves tezepelumab-ekko (Tezspire) for severe asthma

    Author:
    Mark S. Lesney, PhD
    Publish date: December 20, 2021

    “Tezspire represents a much-needed new treatment for the many patients who remain underserved and continue to struggle with severe, uncontrolled...

    • Read More

    News

    No added risk of hepatic cancer in patients with hemophilia after successful HCV treatment

    Author:
    Mark S. Lesney, PhD
    Publish date: October 5, 2021

    “Careful observation is needed in patients with hemophilia even after eradication of HCV.”

    • Read More

    News

    Intracranial hemorrhaging a high risk for patients with hemophilia, especially neonates

    Author:
    Mark S. Lesney, PhD
    Publish date: September 28, 2021

    The observed rates of intracranial hemorrhaging (ICH) in patients with hemophilia were higher compared to the...

    • Read More

    News

    Methylation patterns correlate with prognosis in children with T-ALL

    Author:
    Mark S. Lesney, PhD
    Publish date: September 23, 2021

    Hypomethylation of the asparagine synthase gene was significantly associated with poor therapeutic outcome in children with T-cell acute...

    • Read More

    News

    Transfusions, readmissions higher for patients with CLL after cardiac surgery

    Author:
    Mark S. Lesney, PhD
    Publish date: September 20, 2021

    Most other outcomes were similar for patients with and without CLL, including mortality and infection.

    • Read More

    News

    Can reversing T-cell exhaustion benefit in B-cell lymphoma relapse?

    Author:
    Mark S. Lesney, PhD
    Publish date: September 15, 2021

    Overall, 3 of the 12 patients showed a response after pembrolizumab: One complete response; two partial...

    • Read More

    News

    Genetic shift increases susceptibility to childhood ALL

    Author:
    Mark S. Lesney, PhD
    Publish date: September 9, 2021

    A genetically induced shift toward higher lymphocyte counts was found to increase susceptibility to childhood...

    • Read More

    News

    New gene variant found for hereditary bleeding disorder

    Author:
    Mark S. Lesney, PhD
    Publish date: September 8, 2021

    Reduced expression of thrombomodulin caused by the gene variant may be responsible for the disseminated...

    • Read More

    News

    New treatments have transformed Ph+ acute lymphoblastic leukemia care

    Author:
    Mark S. Lesney, PhD
    Publish date: August 26, 2021

    BCR-ABL mutation tyrosine kinase inhibitors have transformed Ph+ ALL from an historically poor prognosis disease...

    • Read More

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