News
Real-world outcomes of caplacizumab for iTTP comparable to clinical trial results
- Author:
- Mark S. Lesney, PhD
Real-world evidence from the largest series of TTP patients receiving caplacizumab provides confirmation of the...
News
Risk factors predict graft failure in pediatric acute leukemia patients
- Author:
- Mark S. Lesney, PhD
Graft failure is a potentially severe complication in patients treated with allogeneic hematopoietic stem cell...
News
Allo-HSCT plus monoclonal antibody treatment can improve survival in patients with r/r B-ALL
- Author:
- Mark S. Lesney, PhD
Transplantation at 4 months after Mab treatment was initiated showed significant benefits in overall and disease...
News
Updated recommendations released on COVID-19 and pediatric ALL
- Author:
- Mark S. Lesney, PhD
The main threat to the vast majority of children with acute lymphoblastic leukemia still remains the ALL itself...
News
High-dose chemo no better than standard dose for B-cell lymphoma
- Author:
- Mark S. Lesney, PhD
Conventional chemotherapy plus rituximab (R-CHOEP-14) was compared to high-dose chemotherapy plus rituximab...
News
New inhibitor shows promise in previously failed B-cell malignancies
- Author:
- Mark S. Lesney, PhD
Pirtobrutinib (formerly known as LOXO-305) is an oral-dose, highly selective, reversible inhibitor.
News
Prognostic gene signature identifies high- vs. low-risk DLBCL patients
- Author:
- Mark S. Lesney, PhD
The researchers calculated risk scores using their prognostic gene set in three additional published DLBCL studies.
News
CLL, MBL had lower response rates to flu vaccination, compared with healthy adults
- Author:
- Mark S. Lesney, PhD
Patients with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis were assessed for their immune response.
News
Immunoabsorption shows promise as an adjunct treatment for high-risk acquired hemophilia
- Author:
- Mark S. Lesney, PhD
Immunoabsorption therapy targeting factor VIII inhibitors appeared effective, but the researchers suggest that...
News
Ceftolozane-tazobactam found effective in critically ill patients with Pseudomonas aeruginosa infections
- Author:
- Mark S. Lesney, PhD
The primary outcome of the study was to assess the efficacy and toxicity of C/T therapy.
News
CDC: 20% of people in the U.S. are infected with an STD
- Author:
- Mark S. Lesney, PhD
STI incidence was determined using 2018 data and was highest in the 15- to 24 year-old age bracket.
News
First monthly injectable HIV treatment approved by FDA
- Author:
- Mark S. Lesney, PhD
Approval of Cabenuva was based upon two randomized, open-label, controlled clinical trials in 1,182 HIV-infected...
News
Global Ebola vaccine stockpile established
- Author:
- Mark S. Lesney, PhD
The stockpile, which is maintained in Switzerland, is designed to be readily deployed to other countries...
News
Allo-HSCT improves disease-free, but not overall survival in adults with ALL, compared with ped-inspired chemo
- Author:
- Mark S. Lesney, PhD
Allogeneic hematopoietic stem-cell transplantation improved disease-free survival, compared with Berlin-...
News
Eliminating hepatitis by 2030: HHS releases new strategic plan
- Author:
- Mark S. Lesney, PhD
The United States “is currently facing unprecedented hepatitis A outbreaks, while progress in preventing hepatitis B has stalled, and hepatitis C...