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Ultrahigh-Field Imaging Improves Lesion Detection

Neuroimaging Clin N Am; 2017 May; Schindler, et al

Publish date:: April 18, 2017

Ultrahigh-field (UHF) magnetic resonance (MR) imaging, used at many leading academic medical centers to study neurologic disorders, improves multiple sclerosis (MS) lesion detection, with particular sensitivity to detect cortical lesions, according to a recent review. The improved spatial resolution and anatomic detail are due to the increase in signal-to-noise and contrast-to-noise ratio at higher magnetic field strengths. Some key points:

UHF MR imaging enables superior detection of MS abnormalities in the white matter and gray matter.
The detection of the “central vein sign” within MS lesions is improved with UHF MR imaging.
UHF MR imaging provides new insights about the mechanisms of lesion development.
Susceptibility-based MR imaging at UHF may provide new information about the outcome of MS lesions.

Citation:

Schindler MK, Sati P, Reich DS. Insights from ultrahigh field imaging in multiple sclerosis. Neuroimaging Clin N Am. 2017;27(2):357-366. doi:10.1016/j.nic.2016.12.006.

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