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TMS May Provide a Therapeutic Option for Tourette

Brain Sci; 2018 Jul; Grados, Huselid, et al

Transcranial magnetic stimulation (TMS) can be used as an effective tool to explore the psychophysiology of Tourette syndrome (TS) and potentially provide a therapeutic option, a recent study found. Researchers examined all published clinical trials employing TMS to ameliorate tics and that discuss a framework for the pathophysiology of TS in relation to electrical brain activity. They found:

  • Therapeutic electrical brain activity modulation with TMS has been carried out in stroke neuro-rehabilitation and neuropsychiatry, including trials in TS.
  • 11 trials document the use of TMS in TS targeting several brain areas, a positive effect is seen for those trials targeting the insula-supplementary motor area (SMA).
  • In particular, it appears that younger individuals with concurrent attention-deficit hyperactivity disorder (ADHD) benefit the most.

Citation:

Grados M, Huselid R, Duque-Serrano L. Transcranial magnetic stimulation in Tourette syndrome: A historical perspective, its current use and the influence of comorbidities in treatment response. Brian Sci. 2018;8(7);129. doi:10.3390/brainsci8070129.