Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Dietary Sodium and Migraine

Headache; ePub 2016 Mar 26; Pogoda, Gross, et al

Publish date:: April 19, 2016

There may be an inverse relationship between migraine and dietary sodium intake that affects brain extracellular fluid sodium concentrations and neuronal excitability, according to a study of 8,819 adults with reliable data on diet and headache history. Researchers found:

• Odds of probable migraine history decreased with increasing dietary sodium intake (OR=0.93).

• The relationship was maintained, with slightly reduced significance, after adjustments for age, sex, and body mass index (BMI).

• In women, the inverse relationship was limited to those with lower BMI, while in men the relationship did not differ by BMI.

• Researchers likely excluded some migraineurs by omitting frequent analgesic users; but a sensitivity analysis suggested little effect from the exclusion.

Citation: Pogoda JM, Gross NB, Arakaki X, Fonteh AN, Cowan RP, Harrington MG. Severe headache or migraine history is inversely correlated with dietary sodium intake: NHANES 1999–2004. [Published online ahead of print March 26, 2016]. Headache. doi:10.1111/head.12792.

This Week's Must Reads

COVID-19 vaccine found effective but doctors watching for reactions, adverse events,

Study links sleep meds and dementia risk in older adults,

Childhood Hodgkin survivors have neurocognitive impairment,

Obesity, hypoxia predict severity in children with COVID-19,

Long-term safety and efficacy of teriflunomide for relapsing MS,

Must Reads in Headache & Migraine

HIT-6 may help track meaningful change in chronic migraine,

Choroid plexuses may play a role in migraine,

Multiple traits more common in difficult-to-treat patients with migraine,

Marijuana for migraine? Some tentative evidence,

Low vitamin D levels in patients with migraine,