Clinical Inquiries
Clinical Inquiries
Do venlafaxine and gabapentin control hot flashes in women with a history of breast cancer?
EVIDENCE-BASED ANSWER: YES. Venlafaxine reduces hot flashes more than placebo in women with a history of breast cancer; adverse effects include...
Clinical Inquiries
Do any topical agents help prevent or reduce stretch marks?
EVIDENCE-BASED ANSWER: NO TOPICAL AGENT has been proven to prevent or reduce stretch marks. Randomized controlled trials (RCTs) show that cocoa...
Clinical Inquiries
What medications are best for diabetic neuropathic pain?
EVIDENCE-BASED ANSWER: TRICYCLIC ANTIDEPRESSANTS, duloxetine, pregabalin, oxycodone, and tramadol are all effective for the symptomatic treatment...
Clinical Inquiries
What are the benefits and risks of IUDs in adolescents?
EVIDENCE-BASED ANSWER: LITTLE AVAILABLE EVIDENCE specifically addresses the benefits and risks of intrauterine devices (IUDs) in adolescents. Most...
Clinical Inquiries
Which treatments relieve painful muscle spasms from a black widow spider bite?
EVIDENCE-BASED ANSWER: OPIOIDS RELIEVE PAIN and benzodiazepines ease muscle spasms in most patients with latrodectism—widespread, sustained spasms...
Clinical Inquiries
Can calcium supplements cause serious adverse effects in healthy people?
Clinical Inquiries
What treatments relieve painful heel cracks?
EVIDENCE-BASED ANSWER: Emollient cream may alleviate pain and dryness and improve the appearance of heel cracks (strength of recommendation [SOR...
Clinical Inquiries
Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations?
EVIDENCE-BASED ANSWER: YES. Antibiotic use reduced mortality and treatment failure in patients hospitalized with acute exacerbations of chronic...
Clinical Inquiries
Multivitamins for healthy children: What are the true benefits?
EVIDENCE-BASED ANSWER: THE BENEFITS APPEAR TO BE LIMITED. It’s doubtful that multivitamin with mineral (MVM) supplementation improves IQ in...
Clinical Inquiries
Do inhaled steroids reduce bone mineral density and increase fracture risk?
EVIDENCE-BASED ANSWER: NO, except perhaps at high doses. Inhaled corticosteroids (ICS) at low to medium doses (<1500 mcg beclomethasone...
Clinical Inquiries
Intranasal steroids vs antihistamines: Which is better for seasonal allergies and conjunctivitis?
EVIDENCE-BASED ANSWER: INTRANASAL STEROIDS PROVIDE BETTER RELIEF for adult sufferers, according to nonstandardized, nonclinically validated scales...