Key clinical point: The prognosis for patients with breast cancer (BC) who develop contralateral axillary lymph node metastasis (CAM) is similar to that for patients developing oligometastatic disease (OM) but is considerably worse than that for patients developing locoregional recurrence (LRR).
Major finding: The overall survival (OS) and progression-free survival (PFS) outcomes in patients with CAM were similar to those in patients with OM (P = .07 and P = .97, respectively) but were significantly worse than those in patients with LRR (hazard ratio [HR] 0.47, P = .0097; and HR 0.39, P < .0001).
Study details: Findings are from a single-center retrospective study including 299 patients with BC, of whom 29, 180, and 90 patients developed CAM, OM, and LRR respectively.
Disclosures: This study did not receive any specific funding. The authors declared no conflicts of interest.
Source: Zhao Q et al. Contralateral axillary lymph node metastasis in breast cancer: An oligometastatic-like disease. Breast. 2023 (Oct 7). doi: 10.1016/j.breast.2023.103589