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Boxed warning for JAK inhibitors belies their durability in real-world registry studies
JAK inhibitors’ discontinuation and retention rates were similar to those for other biologic disease-modifying antirheumatic drugs, including...
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Real-world data reinforce stem cell transplant for progressive systemic sclerosis
In real-world study, stem cell transplant provides major advantages for rapidly progressive systemic sclerosis if strict selection criteria are...
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Absolute increase in Kawasaki CV risk remains small in long-term follow-up
Relative to controls, the increased long-term cardiovascular risk of patients with Kawasaki disease is small in most patients.
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Delays in NSTEMI hospitalization linked to lower survival
After onset of non-STEMI symptoms, delays in hospitalization are linked to poorer long-term outcomes.
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Daily aspirin linked to increased risk of heart failure
Daily aspirin may need to be reconsidered in those at risk of heart failure, based on evidence of an association.
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Ticagrelor reversal agent achieves quick hemostasis: REVERSE-IT
The monoclonal antibody bentracimab, which can rapidly reverse ticagrelor, was found effective and safe in an FDA-requested interim analysis of a...
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DREAM-HF: Negative stem cell trial in heart failure may still offer promise
Despite zero evidence of benefit on the primary endpoint, stem cell transplant is still promising in heart failure.
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EHRs have no impact on inpatient heart failure clinical choices or outcomes
Relative to usual care, prognostic information at the bedside provided no advantage for heart failure care.
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No advantage shown for LAA ligation as adjunct to pulmonary vein isolation
For AFib control, left atrial appendage ligation is not additive to pulmonary vein ventral isolation at 12 months.
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BP Track: Blood pressure control rates dropped during pandemic
Data culled from 24 health systems showed lower rates of blood pressure control during the COVID-19 pandemic.
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Direct comparison shows differing strengths for left atrial closure devices
For left atrial appendage closure, differences are found between the Amplatzer Amulet and the Watchman FLX in randomized trials.
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At 5 years, iFR found as effective and safe as FFR for guiding PCI intervention
Five-year data reinforce prior finding: iFR and FFR are comparably effective and safe for guiding revascularization.
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Practicing telepsychiatry: Include backup plans, ground rules
Ideally, telepsychiatry will function much like an inpatient office visit, but the dynamics differ – as do the things that can go wrong.
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Short DAPT course beneficial after PCI in ‘bi-risk’ patients
MASTER DAPT subgroup analysis supports short antiplatelet course in cases of high bleeding and ischemic risk.
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SUGAR trial finds superior stent for those with diabetes and CAD
In noninferiority trial, the Cre8 EVO stent was associated with fewer target lesion failures than the Resolute Onyx at 1 year in the setting of...