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Sustained response at 2 years reported for newly approved oral psoriasis agent
Long-term results with the JAK inhibitor for psoriasis show responses persist.
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Targeted anti-IgE therapy found safe and effective for chronic urticaria
Two phase 3 trials associated ligelizumab with efficacy comparable to omalizumab, an approved CSU therapy.
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PARADISE-MI results obscured as post hoc analysis finds flaws
A post hoc analysis of the PARADISE-MI trial suggests relevant benefits are being missed in current trial design.
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Polypodium leucotomos found to reverse AK skin damage
Microscopy at 12 months associated polypodium leucotomos with reversal of skin damage from actinic keratosis.
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AI-assisted reading of echocardiograms readily detects severe aortic stenosis
Moderate and severe aortic stenosis is identified accurately on echocardiograms by artificial intelligence.
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ARBs, beta-blockers independently inhibit Marfan syndrome progression
Compiled data support angiotensin receptor blockers and beta-blockers, alone or together, for Marfan syndrome.
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New ovulatory disorder classifications from FIGO replace 50-year-old system
Once an ovulatory disorder has been diagnosed, four basic categories provide a framework for classification.
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Artificial intelligence poised to change paradigm of CV risk prevention
A new generation causal-based AI algorithm promises to personalize CV risk management to prevent events.
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In blinded trial, artificial intelligence beats sonographers for echo accuracy
In a blinded trial, artificial intelligence provided a more consistent reading of echocardiograms than sonographers.
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Secondary CV prevention benefit from polypill promises global health benefit
In older patients with a prior myocardial infarction, a three-drug polypill significantly reduced risk of CV events in the multinational SECURE...
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Second opinions on melanocytic lesions swayed when first opinion is known
Downward and upward shifts in severity from an accurate diagnosis are concerning because of the likelihood they will lead to overtreatment or...
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How nonadherence complicates cardiology, in two trials
Nonadherence prevents patients from achieving treatment benefits, but it also complicates trial interpretation, suggests subanalyses of MASTER...
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Concerns that low LDL-C alters cognitive function challenged in novel analysis
A Mendelian randomization study appears to exonerate very low LDL-C but not therapies from altering cognition.
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COVID skin manifestations vary by type of variant, U.K. study finds
Omicron and Delta COVID-19 skin manifestations differ, according to large U.K. patient survey.
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Remnant cholesterol captures residual CV risk in patients with T2D
Baseline and follow-up remnant cholesterol levels predict cardiovascular events in patients with type 2 diabetes.