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Single and multifraction SBRT found comparable for lung metastases
A single-fraction regimen and a four-fraction regimen netted essentially the same toxicity and oncologic outcomes at 1 year of follow-up.
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Pathologic CR in HER2+ breast cancer predicts long-term survival
Women who achieved a pathologic complete response with any of three neoadjuvant HER2-targeted regimens had better long-term outcomes.
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Combined features of benign breast disease tied to breast cancer risk
Breast cancer risk was most elevated for women with proliferative benign breast disease with atypia detected on an incident screen.
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Gene signature found similarly prognostic in ILC and IDC
The MammaPrint 70-gene signature may help guide chemotherapy decisions in early-stage invasive lobular carcinoma and invasive ductal carcinoma.
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Study advances personalized treatment for older breast cancer patients
Results of the U.K. Age Gap study may help guide treatment decisions in older patients with estrogen receptor–positive breast cancer.
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Restarting breast cancer screening after disruption not so simple
A strategy for breast cancer screening that resulted in the lowest mortality also required the greatest increase in screening program capacity.
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Gene signature may improve prognostication in ovarian cancer
The 101-gene expression signature, called OTTA-SPOT, improved on age and stage in predicting overall survival.
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Incidence, prognosis of second lung cancers support long-term surveillance
A study using SEER data finds that overall survival of surgically resected second primary lung cancers occurring 4-10 years out is similar to that...
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Early screening may halve breast cancer mortality in childhood cancer survivors
A modeling study supports early breast cancer screening in women with a history of chest radiation.
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Trio of antibodies may enable earlier diagnosis of axSpA
The prevalence of autoantibodies to three novel axSpA peptides was more than twice as high among patients with early disease as among patients...
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DECT has mixed performance in differentiating gout vs. CPPD
In a German cohort study of 30 patients, the noninvasive test had high specificity but only moderate to poor sensitivity.
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New registry focuses on rheumatic immune-related AEs of cancer therapy
Data from the German TRheuMa registry suggest these events are generally mild or moderate, verifiable by CRP level and imaging (but not...
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Studies give new insight on starting, stopping etanercept in nonradiographic axSpA
Pfizer-supported trials may help to define the optimal use of etanercept for nonradiographic disease.