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Combo thrombolytic approach fails to reduce ICH in stroke
Although there were promising signs of a potential reduced bleeding risk in intracranial hemorrhage, the DUMAS study showed no benefit on the...
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Intensive BP lowering harmful in acute ischemic stroke: ENCHANTED2/MT
“This result is not what we expected, but it is a definitive result and gives us a lower safety margin for blood pressure in acute ischemic stroke...
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Collateral flow flags stroke patients for late thrombectomy
The MR CLEAN-LATE trial shows patients selected for thrombectomy on the presence of collateral flow had a greater chance of a better functional...
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SMART-CHOICE 3-year results support dropping aspirin after PCI
The antiplatelet strategy after PCI is currently shifting to reduce the duration of DAPT.
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Aspirin primary prevention benefit in those with raised Lp(a)?
A new analysis of the ASPREE primary prevention trial of aspirin has shown a net clinical benefit in those with genotypes associated with raised...
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Cumulative blood pressure load: A better predictor of CV events?
Cumulative systolic BP load, calculating the magnitude and duration of hypertension from serial measures, may provide better prediction of major...
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Patisiran benefits ATTR amyloidosis with cardiomyopathy: APOLLO-B
More details of the positive results with the RNAi therapeutic on functional capacity and quality of life were reported.
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Artificial sweeteners linked to higher CV event risk
The first study to include artificial sweetener from all sources, not just drinks, may increase concerns about these agents. But not all are...
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Majority of muscle symptoms with statins not caused by treatment
A new Cholesterol Trialists Collaboration meta-analysis shows that in 14 of the 15 people who experience muscle pain or weakness when taking a...
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AXIOMATIC-SSP: Cautious optimism on factor XI inhibitor in stroke
The new factor XI inhibitor antithrombotic, milvexian, showed promising results in a dose-finding phase 2 trial in patients with acute ischemic...
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DANCAVAS misses primary endpoint but hints at benefit from comprehensive CV screening
Comprehensive cardiovascular screening fell short of significantly reducing all-cause mortality in men aged 65-74, but some benefits were seen.
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TIME: CV events similar with evening or morning dose of BP meds
Despite a suggestion that evening dosing may be better, patients who took antihypertensive medication either evening or morning had similar...
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Adding salt to food linked to higher risk of premature death
“An excessive salt intake is harmful in hypertensive patients and increases the risk of stroke. But 0.17 g is not going to make any difference.”...
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New European guidelines ‘drastically’ reduce statin eligibility
“The risk threshold in this new guideline means that almost nobody qualifies for treatment in many countries.”
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Access to certified stroke centers divided by race, income
Access to stroke-certified hospitals is less available in low-income and rural areas of the United States and in Black, racially segregated...