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More evidence of better outcomes with 120–mm Hg BP target
“We are doing very badly in terms of implementation. There is a big gap between science and what’s happening in the real world.”
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Single injection reduces blood pressure for 6 months: KARDIA-1
Zilebesiran is a subcutaneous RNA interference therapeutic that binds with high affinity to the hepatic asialoglycoprotein receptor, bringing...
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Low-salt diet cut BP by 6 mm Hg in 1 week: CARDIA-SSBP
“The blood pressure reduction we see here is ... comparable to that produced by one antihypertensive medication,” said Dr. Deepak Gupta.
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Apixaban cuts stroke but ups bleeding in subclinical AFib: ARTESIA
The big question is whether the reduction in stroke with anticoagulation outweighs the increase in major bleeding.
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Impressive bleeding profile with factor XI inhibitor in AFib: AZALEA
“This gives us real hope that we have finally found an anticoagulant that is remarkably safe,” said Dr. Christian Ruff.
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Semaglutide ‘a new pathway’ to CVD risk reduction: SELECT
The SELECT trial was “a turning point in the treatment of obesity and a call to action.”
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Women have worse outcomes in cardiogenic shock
“Our decision-making around women seems to be different to that around men. I think this paper should start to trigger more awareness of that.”
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AHA joins new cardiovascular certification group ABCVM
The ABIM’s maintenance of certification process has been widely criticized for many years and has been described as “needlessly burdensome and...
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Psychological safety in cardiology training
In medicine at large, there is a stereotype that cardiologists can be “arrogant, unkind, and unwelcoming,” which may discourage new fellows from...
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No benefit of colchicine after stroke, TIA: CHANCE-3
“We require randomized trials with longer follow-up prior to abandoning this potential treatment.”
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Low-risk TAVR studies: Divergent long-term results
“Cardiovascular mortality occurred at a rate of about 1% per year with both therapies, strokes at the rate of 1% per year with both therapies, and...
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COVID coronary plaque infection confirms CV risk
The findings may not only explain the link between COVID and the increased risk of cardiovascular events but mark a starting point for new...
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‘Diagnosis creep’: Are some AFib patients overtreated?
“Risk scores derived when risk variables were described in one way are starting to be applied based on a diagnosis made in a totally different way...
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Pragmatic solutions to ‘catastrophic’ global stroke burden
Recommendations to reduce the global burden of stroke include measures to improve surveillance, prevention, acute care, and rehabilitation.
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Factor XI inhibitors: The promise of a truly safe anticoagulant?
The efficacy data in the phase 3 trials will be key to the success of these drugs. “That is a very important part of the puzzle that is still...