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Changing patterns of morbidity and mortality in HIV disease
Leonard H. Calabrese, DO
R.J. Fassenmeyer Chair of Clinical Immunology, Vice-Chair, Department of Rheumatic and Immunologic Disease, Cleveland Clinic
Address: Leonard H. Calabrese, DO, Department of Rheumatic and Immunologic Disease, A50, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195; calabrl@ccf.org
Dr. Calabrese has indicated that he has a relationship which, in the context of his presentation, could be perceived as a potential conflict of interest; ie, he serves as a consultant for the Immunex, Amgen, SmithKline, Searle, and Schering-Plough corporations.
ABSTRACT
In patients with HIV infection, highly active antiretroviral therapy is improving survival, but at the price of a variety of metabolic side effects. Patterns of morbidity and mortality are changing: the leading cause of death is now kidney or liver failure instead of opportunistic infections.