Lupus & Connective Tissue Diseases
From the Journals
Lupus flares linked to gut bacteria overgrowth
It’s “likely the case” that the pathobiome – with the gut bacteria Ruminococcus blautia gnavus being an important pathobiont – helps to...
Latest News
New guidelines for MTX use in pediatric inflammatory skin disease unveiled
One of the recommendations states that liver biopsy is not indicated for routine monitoring of pediatric patients taking low-dose MTX.
Feature
Does colchicine have a role in treating excess ASCVD risk in patients with chronic inflammatory conditions?
Experts in rheumatology, dermatology, and gastroenterology assess the potential of colchicine 0.5 mg to treat residual risk for atherosclerotic...
Guidelines
New EULAR lupus recommendations advise using biologics, tapering steroids
The 2023 recommendations cover new treatment strategies with more ambitious goals, new data on adverse effects of chronic glucocorticoid use, and...
Conference Coverage
Patient selection key to lowering placebo response rates in lupus clinical trials
High placebo response rates in lupus clinical trials are making it difficult to show treatment effectiveness.
Conference Coverage
Strategies for complete B-cell depletion evolve for patients with lupus nephritis
Growing evidence suggests more complete B-cell depletion in patients with lupus nephritis is associated with a greater likelihood of treatment...
Conference Coverage
Dazodalibep may mitigate Sjögren’s syndrome, but more data are needed
The novel agent targets CD40 ligand and showed promising results in a two-stage, phase 2 clinical trial, particularly for patients with notable...
Conference Coverage
EULAR systemic sclerosis recommendations now include immunosuppressants
The update to 2017 recommendations include targeted synthetic and biologic DMARDs for the first time.
Conference Coverage
Encouraging telitacicept results reported in phase 3 for lupus, phase 2 for Sjögren’s
Results of a phase 3 trial in Chinese patients with systemic lupus erythematosus showed a significantly greater response rate with telitacicept,...
Conference Coverage
Lupus nephritis: Hopes, questions arise for baricitinib
Results from a small, independently funded, double-blind, active-comparator trial suggest that baricitinib could be beneficial in the treatment of...
From the Journals
First prospective study finds pregnancies with Sjögren’s to be largely safe
There was no difference in risk of adverse pregnancy outcomes between women with Sjögren’s and the control group, but these negative outcomes were...