Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
New data further suggest that stress does a number on the CV system
Key clinical point: Severe stress reactions to life events or trauma increase risk for multiple types of cardiovascular disease.
Major finding: Relative to unaffected siblings, patients with stress-related disorders had an elevated risk for any cardiovascular disease during the first year after diagnosis (hazard ratio, 1.64) with some moderation thereafter (HR, 1.29).
Study details: A Swedish population-based cohort study of 136,637 patients with stress-related disorders, 171,314 unaffected full siblings, and 1,366,370 matched unaffected people from the general population.
Disclosures: The authors reported that they had no relevant conflicts of interest. The study was supported by the Icelandic Research Fund, an ERC Consolidator Grant, the Karolinska Institutet, and the Swedish Research Council.
Song H et al. BMJ. 2019 Apr 10. doi: 10.1136/bmj.l1255.