Musculoskeletal Disorders
Conference Coverage
Secukinumab provides clinical benefit in phase 3 juvenile arthritis trial
Phase 3 trial shows secukinumab is effective for enthesitis-related arthritis and juvenile psoriatic arthritis in children.
Conference Coverage
Challenges persist in adolescents with rheumatic disease transitioning to adult care
A successful transition from pediatric to adult rheumatology is crucial to maintain continuity of care for patients with rheumatic disease, but...
Conference Coverage
TNF inhibitors linked to threefold increased risk of psoriasis in JIA patients
Although this study confirms earlier research finding an increased risk of psoriasis after TNF inhibitor exposure, it does not necessarily change...
News
FDA approves mirabegron to treat pediatric NDO
The researchers found that after 24 weeks of treatment, the drug improved the patients’ bladder capacity and reduced the number of bladder wall...
Conference Coverage
Success in achondroplasia spurs testing vosoritide in more growth disorders
The quality of growth achieved with vosoritide in achondroplasia is leading to studies in more growth disorders.
Letters from Maine
Helping parents and children deal with a child’s limb deformity
In most clinic decisions the patient, pretty much regardless of age, should be a full participant in the process.
Feature
Dan Kastner wins Crafoord Prize in Polyarthritis
Dr. Kastner received the award for identifying the mechanisms responsible for familial Mediterranean fever, tumor necrosis factor receptor–...
From the Journals
Greater reductions in knee OA pain seen with supportive rather than flexible shoes
Compared with patients who wore flat flexible shoes, those who wore stable supportive shoes had greater improvement after 6 months.
From the Journals
Data call for biologics trials in undertreated juvenile arthritis subtype
Many children with enthesitis-related arthritis have significant disease burden despite treatment with biologics currently approved for adults...
Conference Coverage
JIA guideline calls for earlier use of targeted therapies
Patients with juvenile idiopathic arthritis can benefit from earlier introduction of biologic DMARDs, an expert consensus panel said.
Conference Coverage
Gene-replacement therapy shows promise in X-linked myotubular myopathy
An investigational gene therapy decreases ventilator dependence and may improve motor development in children with a rare, life-threatening...