Atopic Dermatitis
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Tapinarof effective for AD in patients as young as 2 years
Tapinarof cream, 1%, an aryl hydrocarbon receptor agonist, was approved in 2022 for treating plaque psoriasis in adults.
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Parent concerns a factor when treating eczema in children with darker skin types
For the parent, the pigmentation changes, rather than the inflammation, might be the governing issue and the reason that he or she brought the...
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Lebrikizumab gets European nod for treating moderate-to-severe atopic dermatitis
Lebrikizumab remains under review in the United States.
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AAD updates guidelines for managing AD with phototherapy and systemic therapies
The work group recommended the inclusion of active comparator arms in randomized, controlled trials as new systemic therapies continue to be...
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Review estimates acne risk with JAK inhibitor therapy
Acne has been reported to be an adverse effect of JAK inhibitors, but not much is known about how common acne is overall.
From the Journals
Dupilumab-associated lymphoid reactions require caution
In cases involving unexpected responses or atypical presentations, clinicians must have a low threshold for stopping dupilumab.
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Review finds no CV or VTE risk signal with use of JAK inhibitors for skin indications
Of the 35 trials studied, most involved patients with atopic dermatitis.
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Phase 3 trial supports topical JAK inhibitor for AD in young children
Already approved in adolescents and adults, topical ruxolitinib was found safe and effective in children.
From the Journals
Adolescents with atopic dermatitis more likely to have experienced bullying, study finds
“Clinicians, families, and schools should address and monitor bullying among adolescents.”
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Topical botanical drug coacillium curbs childhood alopecia
Coacillium cutaneous solution is also under investigation as a treatment for persistent chemotherapy-induced alopecia, atopic dermatitis, and...
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Patch testing finds higher prevalence of ACD among children with AD
AD and ACD both present with red, itchy, eczema-like patches and plaques and can be “really hard to differentiate.”