Clinical Edge Journal Scan

PsA-related uveitis: Real-world data on epidemiology and clinical features


 

Key clinical point: Uveitis related to psoriatic arthritis (PsA) had a prevalence of approximately 5%, presented as an acute and recurrent disease with anterior and unilateral involvement, and was associated with impaired quality of life and increased functional disability.

Major finding: Uveitis onset was acute in all cases, with 50% being recurrent and 80% being anterior and unilateral. Patients with vs without uveitis had a higher PsA impact of Disease Score (P = .001) and Bath Ankylosing Spondylitis Functional Index (P = .01) and a higher prevalence of HLA-B27 (P < .0001), sacroiliitis on magnetic resonance imaging (P = .027), and ocular surface pathology (P = .021).

Study details: This retrospective longitudinal study included 406 patients with PsA, of which 4.9% of patients experienced 1 episode of uveitis.

Disclosures: This study did not receive any specific funding. Several authors declared receiving grants, research support, consulting fees, or honoraria for participation in company-sponsored speaker's bureaus from various sources.

Source: De Vicente Delmás A et al. Uveitis in psoriatic arthritis: Study of 406 patients in a single university center and literature review. RMD Open. 2023;9(1):e002781 (Jan 12). Doi: 10.1136/rmdopen-2022-002781

Recommended Reading

Teamwork guides cardio-rheumatology clinics that care for unique patient population
Psoriatic Arthritis ICYMI
Psoriasis, psoriatic arthritis show distinctive skin microbiomes
Psoriatic Arthritis ICYMI
No benefits of concomitant methotrexate in PsA patients treated with ustekinumab
Psoriatic Arthritis ICYMI
Early achievement of minimal disease activity important for long-term benefits in PsA
Psoriatic Arthritis ICYMI
TNFi and increased hematologic malignancy risk in PsA: Is there a link?
Psoriatic Arthritis ICYMI
Residual inflammation may persist despite stable minimal disease activity in PsA
Psoriatic Arthritis ICYMI
Patient-reported flares correlate well with increased disease activity in PsA
Psoriatic Arthritis ICYMI
Fluorescence-optical imaging detects early transition from psoriasis to PsA
Psoriatic Arthritis ICYMI
PsA: Long-term efficacy, persistence, and safety of ustekinumab and TNFi in real world
Psoriatic Arthritis ICYMI
Musculoskeletal ultrasound improves accuracy of early PsA diagnosis
Psoriatic Arthritis ICYMI