Myelodysplastic Syndrome
News
Team links telomere degeneration and MDS
telomeres in green Image by Claus Azzalin New research has revealed a direct link between telomere degeneration and myelodysplastic syndromes (...
News
Drug can alleviate transfusion dependence in non-del-5q MDS
Photo courtesy of Celgene WASHINGTON, DC—Results of a phase 3 trial support the use of lenalidomide in patients with lower-risk myelodysplastic...
News
Inhibitor improves OS in poor-prognosis MDS
WASHINGTON, DC—A small-molecule inhibitor can improve overall survival (OS) in certain patients with previously treated myelodysplastic syndromes...
News
Drug shows promise for lower-risk MDS
WASHINGTON, DC—An investigational drug can increase hemoglobin levels and eliminate transfusion dependence in patients with lower-risk...
News
FDA approves new formulation of deferasirox for iron chelation
News
Understanding the role of del(7q) in MDS
Image by James Thomson A new study has improved researchers’ understanding of a genetic defect associated with myelodysplastic syndromes (MDS),...
Conference Coverage
Iron chelation improves survival in lower-risk MDS
Photo courtesy of ASH SAN FRANCISCO—Iron chelation therapy significantly improves survival for patients with lower-risk myelodysplastic syndrome...
Conference Coverage
Two activin receptor fusion proteins show promise in anemia
site of the ASH Annual Meeting Photo courtesy of ASH SAN FRANCISCO—Two activin receptor fusion proteins, luspatercept and sotatercept, increased...
Conference Coverage
Investigational sotatercept improves heme parameters in MDS
Key clinical point: Sotatercept is a first-in-its-class agent that stimulates erythropoiesis through a mechanism different from that of...
News
Vitiligo, alopecia more likely in GVHD when donor is female and recipient is male
Key clinical point: Female-to-male stem cell donation ups the risk for vitiligo in GVHD. Major finding: 14 of the 15 patients who developed...
News
FDA approves generic decitabine for MDS
Credit: Bill Branson The US Food and Drug Administration (FDA) has approved decitabine for injection, a generic version of Dacogen, to treat...