Follicular Lymphoma
Conference Coverage
Novel agent shows promising activity in heavily pretreated NHL
©ASCO/Rodney White CHICAGO—The novel, oral selective inhibitor of nuclear transport known as selinexor (KPT-330) can safely be given as...
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PET-CT accurately predicts survival of follicular lymphoma patients
Key clinical point: For patients with follicular lymphoma, a PET-CT performed at the end of induction therapy is predictive of survival.Major...
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Agricultural chemicals and the risk of NHL
EPA/John Messina After reviewing nearly 30 years’ worth of data, investigators have compiled a list of agricultural chemicals that appear to...
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Younger men with goiter at higher risk for thyroid cancers
Key clinical point: Men under age 50 undergoing surgery for benign goiter are at elevated risk for thyroid cancer.Major finding: Among men under...
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EC approves SC formulation of rituximab
The European Commission (EC) has approved a subcutaneous (SC) formulation of rituximab (MabThera) to treat patients with follicular lymphoma or...
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Vorinostat demonstrates antitumor activity in FL
Single-agent treatment with the HDAC inhibitor vorinostat can be effective in certain patients with indolent non-Hodgkin lymphoma (NHL), according...
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Anticancer drugs might promote lymphoma
Agents that inhibit tumor growth by targeting the regulatory protein CDK4 might actually promote the growth of B-cell lymphomas, a new study...
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Idelalisib more effective in CLL, iNHL than MCL
Credit: FDA Results of a phase 1 study suggest the PI3K delta inhibitor idelalisib can produce durable responses in certain patients with relapsed...
Conference Coverage
RIT can improve transplant outcomes in NHL, CLL
Ryan Cassaday, MD, of the University of Washington in Seattle, noted that RIT-augmented NMAT can produce long-term remissions in patients with...
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Team identifies mutations that may drive FL
Genetic profiling has provided a clearer picture of follicular lymphoma (FL) development and progression, according to research published in...
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Immune microenvironment linked to prognosis of follicular lymphoma
Major finding: The combination of the number of PMCH- and NAMPT-expressing cells in the interfollicular area plus the interfollicular-to-...