CML
News
Proteins may be therapeutic targets for TKI-resistant CML, ALL
Researchers say they have identified 2 signaling proteins that enable resistance to tyrosine kinase inhibitors (TKIs) and could be therapeutic...
News
Imatinib is safe, effective long-term, team says
Long-term follow-up of patients treated with imatinib suggests the drug can remain effective beyond 10 years and does not confer “unacceptable”...
From the Journals
In CML, imatinib benefits persist at 10 years
Researchers are now reporting the final follow-up results for the IRIS trial after a median of 10.9 years.
News
Acquired mutations may compromise assay
A newly discovered issue with the Ba/F3 transformation assay could “jeopardize attempts to characterize the signaling mechanisms and drug...
News
Group ranks TKIs according to cardiotoxicity
Researchers say they have devised a way to rank tyrosine kinase inhibitors (TKIs) based on their likelihood of causing lasting heart damage in...
News
Styrene exposure linked to myeloid leukemia, HL
A new study links styrene—a chemical used in the manufacture of plastics, rubber, and resins—to certain cancers. The research showed that,...
From the Journals
AML leads percent gains in 5-year survival among leukemias
For 2008-2013, the 5-year relative survival rate for all leukemia was 60.1%, compared with 10% in 1950-1954.
News
Study quantifies 5-year survival rates for blood cancers
A new study shows that 5-year survival rates for US patients with hematologic malignancies have increased greatly since the 1950s, but there is...
News
Drugs may be effective against hematologic, other cancers
Image courtesy of PNAS A diabetes medication and an antihypertensive drug may prove effective in the treatment of hematologic malignancies and...
Conference Coverage
Study reveals CML patients likely to benefit from HSCT long-term
Photo by Chad McNeeley SAN DIEGO—New research may help inform the management of patients with chronic myeloid leukemia (CML), according to a...
News
Group estimates global cancer cases, deaths in 2015
receiving chemotherapy Photo by Rhoda Baer Researchers have estimated the global incidence of 32 cancer types and deaths related to these...