IBD & Intestinal Disorders
Conference Coverage
Upadacitinib shows positive endoscopic outcomes in Crohn’s disease at 1 year
“The absolute magnitude of the finding was unanticipated – a greater treatment effect than might be anticipated for these outcomes compared with...
From the Journals
AI helps predict ulcerative colitis remission/activity, flare-ups
“If this is validated in larger studies, AI can help determine if we should adjust/change therapies or continue, which is very important.”
From the Journals
COVID raises risk for long-term GI complications
“Are patients attributing their symptoms to COVID, or is COVID itself creating a background of inflammation or changes in the nerves that are...
Conference Coverage
AI-assisted colonoscopy in IBD: Not all it’s cut out to be?
The lower ADR rate in AI-assisted procedures could be the result of an overreliance on the AI technology and shorter procedure times, which may...
From the Journals
Patient-based mouse MVID model hints at mechanism
A method using gene editing at the two-cell stage recreated in mice the phenotype of a patient with two separate mutations.
From the AGA Journals
TMEM16A, TMEM16F play crucial role in Paneth cell secretion
Findings from a mouse study could aid developments in anti-inflammatory therapies for intestinal diseases.
Conference Coverage
Crohn’s disease remission rates ‘remarkably higher’ with vedolizumab
Findings may influence physicians to select vedolizumab over anti-TNF therapy as first-line biologic for CD.
Conference Coverage
Mental health risks higher among young people with IBD
“Anxiety and depression will not be a surprise to most of us. But we also saw changes for eating disorders, PTSD, and sleep changes.”
Conference Coverage
DNA panels could predict endoscopic response to biologics in Crohn’s disease
Adding biomarkers to improve biologic medication selection is “urgently needed ... however, such biomarkers are not available for practice today...
From the AGA Journals
Celiac disease appears to double COVID-19 hospitalization risk
“To our knowledge this is the first study that demonstrated a vaccination effect on mitigation of the risk of hospitalization in celiac disease...