Clinical Inquiries
Clinical Inquiries
What is the prognosis for patients with chronic urticaria?
EVIDENCE-BASED ANSWER: THE PROGNOSIS FOR CHRONIC URTICARIA IN PRIMARY CARE IS UNKNOWN; studies in dermatology clinics in multiple countries report...
Clinical Inquiries
What is the best way to treat Morton’s neuroma?
EVIDENCE-BASED ANSWER: NO SINGLE TREATMENT HAS BEEN IDENTIFIED in the literature. That said, a protocol of stepped care that showed good results...
Clinical Inquiries
Which medications benefit patients with diastolic heart failure?
EVIDENCE-BASED ANSWER: Aangiotensin-converting enzyme inhibitors (ACEIs), propranolol, statins, furosemide, and some angiotensin receptor blockers...
Clinical Inquiries
What is the most effective treatment for acne rosacea?
EVIDENCE-BASED ANSWER: TOPICAL METRONIDAZOLE AND AZELAIC ACID are equally effective for the papulopustular lesions of acne rosacea, although...
Clinical Inquiries
Which nutritional therapies are safe and effective for depression?
EVIDENCE-BASED ANSWER: ST. JOHN’S WORT is effective for short-term relief of mild to moderate depression (strength of recommendation [SOR]: A; 1...
Clinical Inquiries
Is cinnamon safe and effective for treating lipid disorders?
EVIDENCE-BASED ANSWER: IT’S PROBABLY SAFE, BUT ITS EFFECTIVENESS IS UNCERTAIN. Insufficient evidence exists to determine whether cinnamon improves...
Clinical Inquiries
Childhood alopecia areata: What treatment works best?
EVIDENCE-BASED ANSWER: IT’S UNCLEAR; there are no validated effective treatments for alopecia areata (AA). Topical immunotherapy (squaric acid...
Clinical Inquiries
Do NSAIDs impede fracture healing?
EVIDENCE-BASED ANSWER: NO, ALTHOUGH THE EVIDENCE VARIES. Nonsteroidal anti-inflammatory drugs (NSAIDs) don’t appear to impair clinical fracture...
Clinical Inquiries
When should you treat tongue-tie in a newborn?
EVIDENCE-BASED ANSWER: CONSIDER TREATMENT WHEN THE INFANT IS HAVING DIFFICULTY BREASTFEEDING. Infants with mild to moderate tongue-tie, or...
Clinical Inquiries
Which patients benefit from lowering LDL to <100 mg/dL?
EVIDENCE-BASED ANSWER: PATIENTS WHO HAVE CORONARY HEART DISEASE (CHD) or are at high risk for CHD should aim for a low-density lipoprotein (LDL)...
Clinical Inquiries
How should we monitor men receiving testosterone replacement therapy?
EVIDENCE-BASED ANSWER: MONITOR HEMATOCRIT AND BONE MINERAL DENSITY (BMD) (strength of recommendation [SOR]: B, meta-analysis of non–patient-...