Rare Diseases

What Is Your Diagnosis? Old World Leishmaniasis

A 22-year-old man who was an army veteran presented with a persistent, tender, ulcerated plaque on the right bicep of 4 months’ duration.

Leishmaniasis is a vector-borne disease caused by protozoan parasites from the genus Leishmania. Disease capabilities arise when sand flies...

Publish date: January 7, 2014

Major finding: In a multivariate analysis, patients negative for minimal residual disease had about a fourfold increased rate of progression-free...

Publish date: November 13, 2013

Major Finding: At median follow-ups of 86 and 73 months, respectively, the HIV-negative group had a 95% rate of freedom from disease progression...

Candidiasis is the most common fungal infection in immunocompromised patients who are at greater risk for developing disseminated disease. Renal...

Although rare, of all the cutaneous lymphoid malignancies, cutaneous T-cell lymphomas (CTCLs) constitute 65% of all lymphomas, of which 50% are...

Congenital infantile fibrosarcoma (CIFS) is a rare pediatric soft tissue tumor; clinically, it presents as a highly vascular mass and may simulate...

Idiopathic thrombocytopenic purpura (ITP) is an acquired autoimmune disorder in which autoantibodies are made against platelets, causing...