Original Research
Original Research
The CLEAR Trial: Results of a Large Community-Based Study of Metronidazole Gel in Rosacea
A phase 4, open-label, multicenter, community-based study was conducted in subjects with mild to moderately severe papulopustular rosacea of...
Original Research
Tretinoin Microsphere Gel 0.1% for Photodamaged Facial Skin: A Placebo-Controlled Trial
Tretinoin microsphere gel (TMG) 0.1% was evaluated as a treatment of photodamaged skin. The study included a 6-month, randomized, double-blinded,...
Original Research
Evaluation of the Efficacy and Safety of Clobetasol Propionate Spray in the Treatment of Plaque-Type Psoriasis
Treatment of the inflammatory component of plaque psoriasis is an important part of psoriasis management.
Original Research
Desoximetasone 0.25% and Tacrolimus 0.1% Ointments Versus Tacrolimus Alone in the Treatment of Atopic Dermatitis
Long-term in vitro compatibility of desoximetasone and tacrolimus ointments prompted the current trial in humans. We aimed to evaluate the...
Original Research
The Safety and Efficacy of Sertaconazole Nitrate Cream 2% for Tinea Pedis
To determine the safety and efficacy of topical sertaconazole nitrate cream 2% in the treatment of tinea pedis, 2 randomized, multicenter, double-...
Original Research
Facilitating Facial Retinization Through Barrier Improvement
The utility of topical tretinoin as a treatment for improving the appearance of photodamaged skin is limited by irritation that occurs during the...
Original Research
Nonlaser UVB-Targeted Phototherapy Treatment of Psoriasis
Nonlaser localized narrowband (290–315 nm) UVB phototherapy was tested in 10 subjects with localized psoriasis. Treatments were given 2 to 3 times...
Original Research
A Survey-Based Assessment of the Prevalence and Severity of Chronic Hand Dermatitis in a Managed Care Organization
Although studies conducted outside of the United States have found a 7% to 12% prevalence of chronic hand dermatitis, no US general population–...
Original Research
The Effect of Simulated Solar UV Irradiation on Tretinoin in Tretinoin Gel Microsphere 0.1% and Tretinoin Gel 0.025%
Topical tretinoin is highly effective and widely used in the treatment of acne vulgaris.
Original Research
Benefits of Mild Cleansing: Synthetic Surfactant-Based (Syndet) Bars for Patients With Atopic Dermatitis
Atopic dermatitis (AD) is a recurring inflammatory skin disease, characterized by marked pruritus, which usually develops in early childhood. AD...
Original Research
Predictors of Healthcare Outcomes and Costs Related to Medication Use in Patients With Acne in the United States
This study investigated the relationship among health status, costs linked with the treatment of acne in the United States, and other aspects...