Original Research
Original Research
Efficacy and Safety Study of Tazarotene Cream 0.1% for the Treatment of Brittle Nail Syndrome
Brittle nail syndrome refers to nails that exhibit surface roughness, raggedness, and peeling. It is a common problem, with a higher prevalence...
Original Research
Randomized Tolerability Analysis of Clindamycin Phosphate 1.2%–Tretinoin 0.025% Gel Used With Benzoyl Peroxide Wash 4% for Acne Vulgaris
The multiple etiologic factors involved in acne vulgaris make the use of several medications necessary to treat the condition.
Original Research
Impact of a Fixed Combination of Clindamycin Phosphate 1.2%–Benzoyl Peroxide 2.5% Aqueous Gel on Health-Related Quality of Life in Moderate to Severe Acne Vulgaris
The acne-specific quality of life (Acne-QoL) questionnaire was developed to measure the impact of facial acne across 4 domains (acne symptoms,...
Original Research
Improvement in Treatment Adherence With a 3-Day Course of Fluocinonide Cream 0.1% for Atopic Dermatitis
Variations in adherence may cause variations in treatment outcomes with topical corticosteroid therapy for atopic dermatitis. An intensive short...
Original Research
Evaluation of a Kojic Acid, Emblica Extract, and Glycolic Acid Formulation Compared With Hydroquinone 4% for Skin Lightening
Hydroquinone has been the standard prescription agent for skin lightening; however, its use recently has become controversial. Hydroquinone is...
Original Research
Simplifying Regimens Promotes Greater Adherence and Outcomes With Topical Acne Medications: A Randomized Controlled Trial
New combination topical formulations for the treatment of acne may improve outcomes by increasing adherence. We assessed adherence to and efficacy...
Original Research
Tretinoin for the Treatment of Photodamaged Skin
Interest in and interventions for photodamaged skin have dramatically increased over the last few years.
Original Research
Sustained Clearance of Superficial Basal Cell Carcinomas Treated With Imiquimod Cream 5%: Results of a Prospective 5-Year Study
We conducted a prospective, multicenter, phase 3, open-label study to assess long-term sustained clearance of superficial basal cell carcinomas (...
Original Research
Fluorouracil Cream 0.5% for Actinic Keratoses on Multiple Body Sites: An 18-Month Open-Label Study
This prospective 18-month, open-label, multicenter study assessed the long-term safety and efficacy of fluorouracil cream 0.5% in 277 participants...
Original Research
Tolerability and Cosmetic Acceptability of Liquor Carbonis Distillate (Coal Tar) Solution 15% as Topical Therapy for Plaque Psoriasis
Although generally recognized as an effective therapy for psoriasis, coal tar therapy lost appeal in modern clinical practice due to poor patient...
Original Research
Fixed-Combination Products in the Management of Acne Vulgaris
Acne vulgaris is the most common dermatologic disorder in the United States. Although its cause is unknown, various factors are implicated in its...