Autoimmune Diseases
Conference Coverage
Lenabasum missed mark for systemic sclerosis but may show promise for adjunctive therapy
The negative trial findings are primarily due to participants’ continued use of background immunosuppressive therapy during the trial, but...
Food for Thought
Reexamining the Role of Diet in Dermatology
The role of diet in acne has been well studied, but rigorous studies on dietary interventions for other common skin conditions are lacking....
Conference Coverage
BEAT-LUPUS: Belimumab after rituximab delays severe flares
Results from a phase 2b trial are “clearly encouraging” and “support the hypothesis that BAFF [B-cell–activating factor] can drive flares after...
Conference Coverage
Intravenous immunoglobulin controls dermatomyositis in phase 3 trial
Intravenous immunoglobulin was safe and effective for dermatomyositis in the first multinational, phase 3, placebo-controlled trial to evaluate...
Case Reports
Ulcerative Heliotrope Rash in Antimelanoma Differentiation–Associated Gene 5 Dermatomyositis
Antimelanoma differentiation–associated gene 5 dermatomyositis (anti-MDA5 DM) can present with an ulcerative heliotrope rash. Ulceration of the...
Case Reports
Psoriatic Alopecia in a Patient With Crohn Disease: An Uncommon Manifestation of Tumor Necrosis Factor α Inhibitors
Psoriatic alopecia is a rare nonscarring alopecia that can present as a complication of treatment with tumor necrosis factor α inhibitors.
News from the FDA/CDC
FDA panel narrowly backs avacopan approval
The FDA is mulling whether to approve avacopan for ANCA-associated vasculitis based largely on a single trial about which the agency staff has...
Conference Coverage
Black patients with cutaneous sarcoidosis may have more systemic and CV disease
Black patients were significantly more likely to have two or more organs involved and have higher rates of cardiac involvement.
Case Letter
Squamous Cell Carcinoma in Hidradenitis Suppurativa Lesions Following Tumor Necrosis Factor α Inhibitors
Consider biopsy of representative lesions in men older than 20 years with moderate to severe disease of the groin and/or buttocks prior to...
From the Journals
COVID-19’s impact on lupus inpatients examined in study
Younger inpatients with COVID-19 and SLE showed higher mortality than did COVID-19 inpatients of similar age from the general population in a...
Case Letter
Candida Esophagitis Associated With Adalimumab for Hidradenitis Suppurativa
There is risk for opportunistic infections with adalimumab, and patients should be monitored closely.