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Clinical Topics & News

Methotrexate Toxicity Induced by Ciprofloxacin Leading to Psoriatic Plaque Ulceration: A Case Report

Cutis. 2013 September;92(3):148-150

By

Faranak Kamangar, MD

Timothy G. Berger, MD

Nasim Fazel, MD, DDS

John Y.M. Koo, MD

We present the case of a 90-year-old woman with psoriasis vulgaris who had been treated with methotrexate for many years. The patient presented with psoriatic plaque ulcerations uniquely limited to the active border as well as acute oral ulcerations and severe gastrointestinal upset after undergoing a course of ciprofloxacin for treatment of a bacterial infection.

Read the Full Article

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Although methotrexate (MTX) is used in several medical specialties including dermatology, rheumatology, and oncology, drug-induced mucocutaneous...
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Psoriasis

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