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Original Research
Mequinol 2%/Tretinoin 0.01% Solution: An Effective and Safe Alternative to Hydroquinone 3% in the Treatment of Solar Lentigines
Cutis. 2004 November;74(5):319-322
By
Jarratt M
Author and Disclosure Information
Jarratt M

A new topical solution containing 4-hydroxyanisole (mequinol) 2%/tretinoin 0.01% (Solagé®) was compared with its active components, its vehicle, and hydroquinone (HQ) 3% in the treatment of solar lentigines. In a randomized, parallel-group, double-masked study, 216 subjects applied the treatments twice daily for 16 weeks and were followed up for a further 24 weeks. A significantly higher proportion (P