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Article

Leukocytoclastic Vasculitis Induced by Use of Glyburide: A Case of Possible Cross-Reaction of a Sulfonamide and a Sulfonylurea

Cutis. 2003 March;71(3):235-238

By

Author and Disclosure Information

Bukhalo M, Zeitouni NC, Cheney RT

Drug-induced leukocytoclastic vasculitis (LCV) may present as the result of a single offending agent or more uncommonly, from a cross-reaction with a related medication. We describe a patient with sulfonamide allergy who developed LCV after exposure to a sulfonylurea. Sulfur-containing drugs may cross-react to induce LCV in susceptible individuals.

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