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Pediatric Dermatology
Papular Acrodermatitis of Childhood: The Gianotti-Crosti Syndrome
Cutis. 2001 April;67(4):291-294
Author and Disclosure Information
Belaviciené G, Maciuleviciené R, Schwartz RA

Papular acrodermatitis of childhood (PAC), also known as Gianotti-Crosti syndrome, is a self-limited disorder with acute onset generalized lymphadenopathy and monomorphic lentil-sized, dense, nonconfluent, symmetric, flat-topped, nonpruritic papules. We describe 2 patients, one with anicteric hepatitis, lymphocytosis, and positive hepatitis B surface antigenemia, and the other with a cytomegalovirus (CMV) infection.