Conference Coverage
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Conference Coverage
Noninvasive EEG may speed diagnosis of West syndrome
BANGKOK – High-frequency oscillations are considered a top candidate as long-sought potential biomarker for epilepsy.
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Conference Coverage
Transdermal estradiol may modulate the relationship between sleep, cognition
LOS ANGELES – Women using the patch fared better in all measures than did those taking oral conjugated equine estrogen.
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Conference Coverage
Efficacy of erenumab is sustained over more than 4 years of treatment
PHILADELPHIA – Among patients with episodic migraine, 4.5 years of preventive treatment with erenumab is effective, safe, and well tolerated,...
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Conference Coverage
Benzodiazepines, hypnotics don’t increase Alzheimer’s pathology
LOS ANGELES – The drugs were not associated with Alzheimer’s pathology, but were associated with a trend toward greater loss of neurons in the...
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Conference Coverage
Ubrogepant shows acute migraine efficacy in triptan nonresponders
PHILADELPHIA – Data from two ubrogepant pivotal trials showed similar migraine pain relief in triptan-ineffective and triptan-effective patients...
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Conference Coverage
Galcanezumab benefits patients with migraine and medication overuse
PHILADELPHIA – The monoclonal antibody effectively reduces the number of monthly migraine headache days and...
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Conference Coverage
‘Pot’ is still hot for Dravet, Lennox-Gastaut
BANGKOK – Long-term extension studies show sustained, consistent seizure reductions.
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Conference Coverage
A practical tool predicts childhood epilepsy diagnosis
BANGKOK – The predictor is freely available online.
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Conference Coverage
Intranasal midazolam as first line for status epilepticus
BANGKOK – “Time is brain,” said Dr. Lara Kay.
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Conference Coverage
A new beverage aims to make ketogenic diets more palatable
BANGKOK – Designed to be consumed with regular foods, this beverage shows preliminary evidence of an antiseizure effect.
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Conference Coverage
Neurologists need not discourage breastfeeding in women with MS
STOCKHOLM – For women with MS who want to breastfeed and have more active disease where early treatment resumption is warranted, the key is to...
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Conference Coverage
Ponesimod reduces annualized relapse rate, compared with teriflunomide
STOCKHOLM – The investigational MS treatment is superior to the approved drug on measures of fatigue and active...
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Conference Coverage
Inebilizumab looks good for neuromyelitis optica in phase 2/3 trial
STOCKHOLM – Attacks were significantly reduced and a marker for tissue damage dropped, but IgG levels will likely have to be tracked long term.
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Conference Coverage
Newer drugs provide superior disease activity control in pediatric MS
STOCKHOLM – Study from U.S. Network of Pediatric MS Centers supports early use of newer disease-modifying therapies.
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Conference Coverage
Ofatumumab has superior efficacy in relapsing-remitting MS, compared with teriflunomide
STOCKHOLM – The monoclonal antibody reduced annualized relapse rate and the risk of confirmed disability worsening,...
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Conference Coverage
Plasma exchange in natalizumab-related PML shows no benefit, possible harm
STOCKHOLM – Biggest-ever study of natalizumab-associated PML in patients with multiple sclerosis raises red flag regarding common practice of...
Latest News
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From the Journals
Hemoglobin levels are associated with long-term dementia risk
Both low and high levels of hemoglobin are linked with an increased risk of dementia, according to a population-based study of adults in the...
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News from the FDA/CDC
FDA approves Wakix for excessive daytime sleepiness
The efficacy of pitolisant (Wakix) was evaluated in a pair of multicenter, randomized, double-blind, placebo-controlled studies.
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From the Journals
Prices, out-of-pocket costs for MS drugs rose despite competition
Rather than decreasing prices, the introduction of new self-administered therapies after 2009 may have contributed to increased prices.
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News from the FDA/CDC
FDA approves istradefylline for Parkinson’s disease
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From the Journals
Tandem transplants provide EFS edge in pediatric neuroblastoma
Patients randomized to tandem stem cell transplants after successful induction therapy had fewer events than patients assigned to single...
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From the Journals
‘Fast MRI’ may be option in TBI screening for children
Technique avoids sedation and could be an alternative to CTs, which pose radiation risk.
Guidelines
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Guidelines
Pediatric, adolescent migraine treatment and prevention guidelines are updated
The guidelines review both pharmacologic and nonpharmacologic options, which have multiplied since the previous guidelines were released in 2004...
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Guidelines
AAN guideline encourages vaccinations for MS patients
Unless there are specific contraindications, clinicians should advise patients to follow local vaccine standards, the guideline says.
Literature Review
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Literature Review
Blood test may reveal brain injury
Levels of glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1) are lowest in patients with nonconcussive body...
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Literature Review
Is serum serotonin level associated with risk of seizure-related breathing dysfunction?
A prospective study of patients with intractable epilepsy may indicate physiologic changes that protect against phenomena that lead to SUDEP.
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Literature Review
Migraines linked to higher risk of dementia
People with a history of migraines may be at greater risk of developing Alzheimer’s disease and dementia.
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Literature Review
Can a novel steroidal anti-inflammatory drug benefit patients with Duchenne muscular dystrophy?
Vamorolone may reduce “safety concerns typically seen with traditional glucocorticoids,” researchers said.