News
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Article
DEA Reclassifies Epidiolex as Schedule V
WASHINGTON, DC—The Drug Enforcement Administration (DEA) has reclassified Epidiolex, an oral cannabidiol (CBD) solution...
Conference Coverage
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Conference Coverage
Which Treatments Are Effective Against Intractable Cluster Headache?
ASHEVILLE, NC—Patients with intractable cluster headache present an urgent challenge to neurologists....
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Conference Coverage
Migraine Elevates the Risk of Perioperative Stroke
ASHEVILLE, NC—The 30 days after surgery are a period of exceptionally high...
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Conference Coverage
Controlling Estrogen Levels May Treat Menstrual Migraine
ASHEVILLE, NC—Menstrual-related migraine (MRM) can be particularly disabling and is difficult...
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Conference Coverage
Can the 2017 McDonald Criteria Diagnose MS in Children?
BERLIN—Applying the 2017 McDonald criteria to children is feasible and allows an earlier diagnosis of multiple sclerosis...
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Conference Coverage
MRI Measure Distinguishes MS From Migraine
BERLIN—Gray matter–white matter (GM/WM) contrast ratio on T1 magnetization prepared rapid gradient echo (MPRAGE) is...
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Conference Coverage
Vitamin D Augments Glucocorticoid Efficacy
BERLIN—Vitamin D increases the therapeutic effects of glucocorticoids via an mTORc1–dependent upregulation of the...
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Conference Coverage
Triggers May Guide Treatment of New Daily Persistent Headache
ASHEVILLE, NC—New daily persistent headache is rare and difficult to treat. Although neurologists may be tempted to try...
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Conference Coverage
Researchers Develop Guidelines for Evaluating Cognitive and Behavioral Syndromes in Adults
CHICAGO—An Alzheimer’s Association workgroup has developed 20 recommendations for the clinical...
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Conference Coverage
Level of Serum Neurofilament Light Enables Treatment Monitoring
BERLIN—Serum neurofilament light chain (sNfL) levels are clinically relevant, and data suggest cut points to enable...
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Conference Coverage
Periventricular Lesions Are Associated With Cortical Thinning in MS
BERLIN—Research supports the previously observed association of periventricular lesions with cortical thinning in...
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Conference Coverage
When Is the Optimal Time to Start Treatment in Patients With Relapsing-Remitting MS?
BERLIN—Data from the Big Multiple Sclerosis Data (BMSD) Network indicate that the optimal time to start disease-...
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Conference Coverage
Do Dimethyl Fumarate and Teriflunomide Have Equivalent Efficacy?
BERLIN—Dimethyl fumarate and teriflunomide have similar efficacy in terms of risk of relapse and worsening of Expanded...
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Conference Coverage
Predicting Disability Following Clinically Isolated Syndrome
BERLIN—Smoking and low vitamin D levels are key modifiable prognostic factors that show a significant interaction with...
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Conference Coverage
Ongoing Neuronal Loss Is Greater in Secondary Progressive MS Than Primary Progressive MS
BERLIN—Levels of neurofilament light chain (NfL) indicate that patients with secondary progressive...
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Conference Coverage
To Escalate or Not to Escalate MS Therapy After Relapses?
BERLIN—Relapse-induced escalation to a highly effective disease-modifying therapy (DMT) is associated...
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Conference Coverage
Long-Term Follow-Up of Ocrelizumab-Treated Patient With Relapsing MS
BERLIN—Switching from interferon beta-1a to ocrelizumab after two years at the start of the OPERA I and OPERA II open-...
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Conference Coverage
Is a Unidimensional Cognitive Screen Sufficient for Patients With MS?
BERLIN—Cognitive impairment in patients with multiple sclerosis (MS) varies in presence and...
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Conference Coverage
What Are the Characteristics of Children With Poststroke Headache?
CHICAGO—Among children with pediatric stroke, older age at stroke onset, unilateral infarct location,...
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Conference Coverage
Home-Based Therapy May Benefit Young Children With Motor Stereotypies
CHICAGO—Home-based, parent-administered behavioral therapy supplemented by telephone contact with a therapist is...
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Conference Coverage
High-Dose Biotin for Progressive MS: Real-World Experience
BERLIN—MD1003, a high-dose pharmaceutical grade biotin, is effective in the treatment of patients with progressive...
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Conference Coverage
Smartphone Versus Holter Monitoring for Poststroke Atrial Fibrillation Detection
MONTREAL—In patients hospitalized for a recent acute ischemic stroke or transient ischemic attack (TIA), a smartphone-...
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Conference Coverage
IV Dihydroergotamine Is Associated With Chest Pain in Pediatric Patients With Headache
CHICAGO—Among pediatric patients who receive IV dihydroergotamine (DHE) for headache, chest pain is a common side effect...
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Conference Coverage
High Systemic Inflammation at Midlife Portends Cognitive Changes in Later Life
ATLANTA—Individuals with higher levels of systemic inflammation during midlife experience...
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Conference Coverage
TIA and Stroke May Affect Risk of Subsequent Events Differently in Patients With Atrial Fibrillation
MONTREAL—Neurologists usually consider stroke and transient ischemic attack (TIA) to indicate a similar need for...
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Conference Coverage
Mood Disorders May Worsen Multiple Sclerosis Disability
BERLIN—Depression and bipolar disorder are major risk factors for worsening disability in people with multiple sclerosis...
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Conference Coverage
How Long Should Dual Antiplatelet Therapy Last After Stroke or TIA?
MONTREAL—The optimal length for dual antiplatelet therapy (DAPT) in patients with mild stroke or transient ischemic...
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Conference Coverage
Rapid Sequence MRI May Hold Advantages for Neonates With Seizures
CHICAGO—Use of rapid sequence MRI in the evaluation of neonates with seizures and no hypoxic-ischemic...
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Conference Coverage
No Elevated Cancer Risk With MS Therapies in COMBAT-MS Data
BERLIN—The risk of cancer, and breast cancer in particular, was not elevated above background levels in...
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Conference Coverage
Study Explores Link Between GERD and Poor Sleep Quality
ATLANTA—Chronic gastroesophageal reflux disease (GERD) is associated with various sleep disorders that might complicate...
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Conference Coverage
Vitamin D Levels at Onset Predict Subsequent Cognition in MS
BERLIN—Higher vitamin D levels at multiple sclerosis (MS) onset predict higher cognitive function 11 years later,...
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Conference Coverage
Clinical Scoring System May Help Diagnose Acute Flaccid Myelitis
CHICAGO—Use of the CDC case definition for acute flaccid myelitis may lead to misdiagnosis in patients...
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Conference Coverage
Conference News Roundup—American Association of Neuromuscular & Electrodiagnostic Medicine
Literature Review
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Literature Review
Cognitive and Behavioral Problems Increase With ALS Disease Stage
Cognitive deficits and behavioral symptoms that are specific to amyotrophic lateral sclerosis (ALS) occur more...
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Literature Review
Novel Nordic Study Reveals Diclofenac’s Cardiovascular Risks
In the largest analysis ever of cardiovascular risk associated with the initiation of nonsteroidal anti-inflammatory...
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Literature Review
Modeling Favors Immediate AED Treatment After an Unprovoked First Seizure
Immediate treatment of a first unprovoked seizure may be preferable to delayed treatment over a wide range of patients,...
News Roundup
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News Roundup
New and Noteworthy Information—November 2018
In patients with acute stroke with an unknown time of onset, IV alteplase guided by a mismatch between diffusion-weighted imaging and fluid-...