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Atezolizumab plus chemotherapy superior to best supportive care in early lung cancer
Interim DFS analysis shows that relapse was higher among patients receiving best supportive care, compared with patients who received atezolizumab...
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Combination treatment shows promise for men with advanced prostate cancer
The combination of nivolumab and rucaparib in a clinical trial showed clinical activity for metastatic prostate cancer cases with BRCA mutations....
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Datopotamab deruxtecan for advanced NSCLC encouraging so far
The ongoing TROPION-PanTumor01 clinical trial shows an overall response rate of 35% for patients with advanced or metastatic NSCLC.
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TULIP trial shows extended survival in HER2+ metastatic breast cancer
Progression-free survival was up to 7 months in some cases, but with adverse events.
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ctDNA may be a better surrogate for survival than RECIST
ctDNA was detected in most patients with metastatic uveal melanoma. Treatment with tebentafusp was associated with a reduced tumor burden in 70%...
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Intracranial atherosclerosis finding on MRA linked to stroke
An incidental diagnosis of intracranial atherosclerotic stenosis in stroke-free individuals should trigger a thorough assessment of vascular...
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Superior survival with sintilimab in squamous NSCLC
Sintilimab improved overall and progression-free survival, when compared with docetaxel.
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Tislelizumab bests docetaxel in NSCLC
Tislelizumab was associated with better outcomes in patients with locally advanced or metastatic non–small cell lung cancer.
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Antibiotics may prolong PFS in HCC patients on immunotherapy
Prior studies suggested that antibiotics reduce the efficacy of immunotherapy.
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Tebentafusp improves OS: A first in metastatic uveal melanoma
Tebentafusp prolonged overall survival by nearly 6 months.
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Personalized cancer vaccine shows early promise across tumor types
The vaccine consists of patient-specific synthetic neoantigen peptides and is given to patients in the adjuvant setting.
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Healthy lifestyle may offset genetic risk in prostate cancer
In men at the highest risk of dying from prostate cancer, a healthy lifestyle cut the risk of fatal disease in half.
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Black nonsmokers still at high risk for secondhand smoke exposure
The prevalence of SHS exposure among nonsmokers declined from 87.5% to 25.3% between 1988 and 2012.
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Is the WHO’s HPV vaccination target within reach?
The WHO’s goal is to have HPV vaccines delivered to 90% of all adolescent girls by 2030.