Mitchel is a reporter for MDedge based in the Philadelphia area. He started with the company in 1992, when it was International Medical News Group (IMNG), and has since covered a range of medical specialties. Mitchel trained as a virologist at Roswell Park Memorial Institute in Buffalo, and then worked briefly as a researcher at Boston Children's Hospital before pivoting to journalism as a AAAS Mass Media Fellow in 1980. His first reporting job was with Science Digest magazine, and from the mid-1980s to early-1990s he was a reporter with Medical World News. @mitchelzoler
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Empagliflozin favorably reshaped left ventricles in HFrEF patients
Results from two separate randomized studies showed empagliflozin treatment of patients with HFrEF produced significant heart remodeling.
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New eGFR equation ‘less biased’ by age, kidney function; some disagree
The European Kidney Function Consortium equation surpasses existing equations by "resulting in generally lower bias across the spectrum of age and...
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Novel drug slows progression of diabetic kidney disease
Finerenone, a selective, nonsteroidal mineralocorticoid receptor antagonist, significantly reduced both renal and cardiovascular events, with good...
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Experts tout immediate quadruple therapy for HFrEF patients
Recent evidence cemented four drug classes as foundational pillars of HFrEF treatment. The answer to how to start them: immediately and all at...
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Entresto halves renal events in preserved EF heart failure patients
The PARAGON-HF trial of sacubitril/valsartan in patients with heart failure with preserved ejection fraction didn’t meet its primary outcome but...
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T2D treatments create tension between glycemic and cardiovascular goals
Recent society guidelines clash on whether metformin or newer drug classes should start first when treating patients with type 2 diabetes.
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Adrenal vein sampling looms as choke point for aldosteronism assessment of hypertensives
Imaging’s surprising unreliability for finding unilateral adrenal adenomas leaves pricey and hard-to-run adrenal vein sampling the only option.
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Empagliflozin cut PA pressures in heart failure patients
The drops in pulmonary artery pressure were modest but large enough to be clinically meaningful, they appeared quickly, and increased over time....
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Music’s charms may soothe heart failure’s effects
Evidence builds that music, either heard or sung, exerts measurable benefits for heart failure and other cardiovascular diseases.
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Dapagliflozin’s CKD performance sends heart failure messages
The recently reported DAPA-CKD trial results focused on patients with renal disease, but the findings also resonate for heart failure clinicians...
