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Narcolepsy med shows early promise for adult ADHD
Solriamfetol is a dopamine and norepinephrine reuptake inhibitor that shares some of the properties of current ADHD medications.
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Doublet therapy ups survival in metastatic prostate cancer
“A clinically meaningful increase in long-term survival was observed in men diagnosed with de novo [metastatic castration-sensitive prostate...
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Antibiotics ‘like gold’ for some, driving inappropriate use
Many felt they “knew their body, knew what they had, and knew how to treat themselves” without a health care provider.
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FDA approves new drug for ulcerative colitis
The approval of etrasimod was based on safety and efficacy data from two randomized, double-blind, placebo-controlled phase 3 trials.
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New RSV vaccine will cut hospitalizations, study shows
With widespread use of the vaccine, annual hospitalizations resulting from infant RSV would fall by 51%, emergency department encounters would...
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Wastewater can signal upswing in flu, RSV
The new study shows that wastewater-based surveillance is a “robust and adaptable” tool for community-level surveillance of seasonal respiratory...
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Breast reconstruction post mastectomy: What matters most to women?
“This study provides information on how women value different aspects of their care when making decisions for breast reconstruction.”
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ADHD rates holding steady in U.S. children
The estimated ADHD prevalence remains “high” and “further investigation is warranted to assess potentially modifiable risk factors and provide...
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FDA denies approval for patisiran in ATTR cardiomyopathy, despite panel nod
The FDA indicated in the letter that the clinical meaningfulness of patisiran’s treatment effects for the cardiomyopathy of ATTR amyloidosis have...
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Redefining CVD risk: Cardiovascular-kidney-metabolic (CKM) syndrome
“Clearly defining the patient with CKM syndrome, and providing new approaches for CKM syndrome staging and risk prediction, will help health care...
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MASLD linked to increased risk for various clinical outcomes
The disease significantly raises the risk for cardiovascular, metabolic, oncologic, and other outcomes.
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A new clue into the cause, spread of Parkinson’s disease?
The study demonstrates “for the first time how damaged mitochondrial DNA can underlie the mechanisms of PD initiation and spread in brain,” the...
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Early-onset NAFLD tied to higher cancer risk
Among adults younger than 45 at NAFLD onset, cancers were mainly digestive and lung cancers.
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Loneliness tied to increased risk for Parkinson’s disease
The association between loneliness and incident PD was not moderated by sex, age, or polygenetic risk score.
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USPSTF should reconsider recommendation to lower mammogram age: Experts
The benefit is arguably small, while the harms appear quite significant.