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Semaglutide 2.4 mg ‘likely to usher in a new era’ in obesity treatment
Clinical experience with this drug will grow rapidly over the next few years, one expert predicts, and new combination drugs are near, so...
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Time-restricted eating ‘promising, but more data are needed’
“Time-restricted eating is promising because of its simple message and noted weight-loss benefit, yet more data are needed,” says an expert.
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Bariatric surgery tied to 22% lower 5-year stroke risk
This study contributes to knowledge that suggests that reduction in ischemic stroke risk is yet another benefit of bariatric surgery, says a study...
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Eat two fruits a day, ward off diabetes?
Results from an observational study “support encouragement of the consumption of whole fruits, but not fruit juice, to preserve insulin...
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New obesity target? Dopamine circuit in brainstem affects satiety
A newly identified dopaminergic neural circuit in the hindbrain plays a role in satiety, a mouse study found, which methylphenidate acts on.
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FDA approves ‘game changer’ semaglutide for weight loss
Based on the STEP clinical trial results, the FDA has approved a 2.4 mg/week subcutaneous dose of the GLP-1 receptor agonist semaglutide (Wegovy,...
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A simple new definition for ‘metabolically healthy obesity’?
‘Our new definition may be important not only to stratify risk of mortality in people with obesity, but also in people with overweight and normal...
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Being overweight ups risk of severe COVID-19 in hospital
This research “adds to the known data on the associations between obesity and severe COVID-19 disease and extends these findings” to patients who...
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Severe obesity persists, takes high cardiovascular toll
“This research highlights the high cardiovascular toll exacted by continuing failure to tackle obesity, particularly among more socioeconomically...
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Eating more fat may boost borderline low testosterone
“If somebody has low testosterone, particularly borderline, they could try increasing their fat intake, maybe on a Mediterranean diet, and see if...
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Bariatric surgery may cut cancer in obesity with liver disease
Among working adults with severe obesity and fatty liver disease, rates of cancer were lower after bariatric surgery during a 10-month median...
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‘Major update’ of BP guidance for kidney disease; treat to 120 mm Hg
“[Chapter one] of the guidelines is devoted to blood pressure measurement ... if [targeting] 120 [mm Hg systolic], the emphasis is on 120 measured...
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Semaglutide for meaningful weight loss in obesity and diabetes?
“This is by far the best result we had with any weight loss medicine in patients with diabetes,” says the senior author of the STEP 2 clinical...
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Semaglutide for weight loss? A good first STEP, with caveats
“On the face of it, the STEP 1 trial (like its name) is a good beginning,” said the editorialists. More patients in the semaglutide group had...