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    • Deprecated function: Return type of DatabaseStatementBase::execute($args = [], $options = []) should either be compatible with PDOStatement::execute(?array $params = null): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2246 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::current() should either be compatible with Iterator::current(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::next() should either be compatible with Iterator::next(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::key() should either be compatible with Iterator::key(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::valid() should either be compatible with Iterator::valid(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).
    • Deprecated function: Return type of DatabaseStatementEmpty::rewind() should either be compatible with Iterator::rewind(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in require_once() (line 2348 of /var/www/webmd/apps/mdedge/htdocs/includes/database/database.inc).

    M. Alexander Otto, MMS, PA

    News

    Fifth COVID shot recommended for patients with cancer

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: April 28, 2022

    A fifth shot of an mRNA vaccine represents a second booster because the primary mRNA immunization series for...

    • Read More

    News

    ctDNA unreliable for detecting CRC recurrence after surgery

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: March 23, 2022

    Two ctDNA tests used for this purpose are marketed in the United States.

    • Read More

    News

    FDA approves new immunotherapy combo for metastatic melanoma

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: March 22, 2022

    Approval is based on findings that show median progression-free survival of 10.1 months.

    • Read More

    News

    As predicted: jump in metastatic prostate cancer diagnoses

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: March 16, 2022

    Concerns over unnecessary prostatectomies took precedence over the benefits of screening for early high-risk disease.

    • Read More

    News

    Wake Forest Cancer Center director fired, advisory board resigns

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: March 9, 2022

    The mass resignation of an EAB, a panel of outside experts that help shepherd cancer centers through the NCI grant process, is “highly unusual.”...

    • Read More

    News

    Active surveillance or maintenance after chemo induction in metastatic CRC?

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: March 8, 2022

    Although maintenance strategies have typically demonstrated a PFS benefit, that advantage may come at “the expense of ongoing ... toxicity.”

    • Read More

    News

    Women at higher risk of serious adverse events from cancer therapy

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: February 17, 2022

    As cancer treatment becomes increasingly individualized, “sex may be an important consideration.”

    • Read More

    News

    Increase in late-stage cancer diagnoses after pandemic

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: February 16, 2022

    “Patients who have delayed preventative care during the pandemic should be encouraged to resume treatment as soon as possible.”

    • Read More

    News

    New PET tracer detects more metastases in cancer patients

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: February 8, 2022

    “This may also mark the arrival of a new era in nuclear medicine where molecular imaging helps visualize and characterize the entire tumor burden...

    • Read More

    News

    EMA panel endorses two cancer drugs, one sickle cell drug

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: January 3, 2022

    Tepotinib for NSCLC, enfortumab vedotin for urothelial cancer and voxelotor for sickle cell disease are currently approved in the U.S.

    • Read More

    News

    Voxelotor for sickle cell anemia now down to 4-year-olds

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: December 20, 2021

    Voxelotor for hemolytic anemia in sickle cell disease can now be used in children from 4 years old and is also...

    • Read More

    News

    Risk for breast cancer recurrence persists past 30 years

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: November 18, 2021

    For the first time, new data show that risk for breast cancer recurrence extends...

    • Read More

    News

    ‘First reliable estimate’ of breast cancer metastasis

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: November 8, 2021

    The overall risk of metastasis is between 6% and 22%, with younger women having a higher risk.

    • Read More

    News

    Luminal, basal groupings could change metastatic prostate cancer treatment

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: October 5, 2021

    “These subtypes represent a potentially powerful tool for personalized therapeutic decision-making that may improve outcomes in metastatic mCRPC...

    • Read More

    News

    Watchful waiting in BCC: Which patients can benefit?

    Author:
    M. Alexander Otto, MMS, PA
    Publish date: September 22, 2021

    A study published in JAMA Dermatology sheds light on which patients with BCC may be appropriate candidates for watchful waiting.

    • Read More

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