Article
Do statins increase the risk of developing diabetes?
- Author:
- Kristin Parker, DO
- Karen Dohr, PharmD
- Jon O. Neher, MD
- Gary Kelsberg, MD
- Leilani St. Anna, MLIS, AHIP
EVIDENCE-BASED ANSWER: Yes. Statin therapy produces a small increase in the incidence of diabetes: one additional case per 255 patients taking...
Article
What therapies alleviate symptoms of polycystic ovary syndrome?
- Author:
- Laura “Eli” Moreno, MD
- Ashley Bonnell, PharmD
- Jon O. Neher, MD
- Sarah Safranek, MLIS
EVIDENCE-BASED ANSWER: Treatment of polycystic ovary syndrome (PCOS) in women not actively seeking to become pregnant is symptom-specific....
Article
How do hydrochlorothiazide and chlorthalidone compare for treating hypertension?
- Author:
- Leanne Kildare, MD
- Ty Jones, MD
- Jon O. Neher, MD
- Leilani St. Anna, MLIS, AHIP
EVIDENCE-BASED ANSWER: Both medications reduce theincidence of cardiovascular events in patients with hypertension, but chlorthalidone may confer...
Article
Do venlafaxine and gabapentin control hot flashes in women with a history of breast cancer?
- Author:
- Angela Sarkissian, MD
- Jon O. Neher, MD
- Ravipal Singh, PharmD
- Leilani St. Anna, MLIS, AHIP
EVIDENCE-BASED ANSWER: YES. Venlafaxine reduces hot flashes more than placebo in women with a history of breast cancer; adverse effects include...
Article
Multivitamins for healthy children: What are the true benefits?
- Author:
- Heather Schouweiler, MD
- Jon O. Neher, MD
- Leilani St. Anna, MLIS, AHIP
EVIDENCE-BASED ANSWER: THE BENEFITS APPEAR TO BE LIMITED. It’s doubtful that multivitamin with mineral (MVM) supplementation improves IQ in...
Article
Medication vs radioablation for Graves’ disease: How do they compare?
- Author:
- Justin Ford, MD
- Jon O. Neher, MD
- Sarah Safranek, MLIS
EVIDENCE-BASED ANSWER: THE BENEFITS ARE SIMILAR; the risks vary. Treating Graves’ disease initially with medication or radioablation (or surgery)...
Article
What drugs are effective for periodic limb movement disorder?
- Author:
- Yuri A. Lee, MD
- Philip Huynh, PharmD
- Jon O. Neher, MD
- Sarah Safranek, MLIS
EVIDENCE-BASED ANSWER: CLONAZEPAM improves subjective sleep quality and polysomnogram (PSG) measures of leg movements more than placebo (strength...
Article
How does smoking in the home affect children with asthma?
- Author:
- Tina Neogi, MD
- Jon O. Neher, MD
- Sarah Safranek, MLIS
EVIDENCE-BASED ANSWER: CHILDREN WITH ASTHMA who are exposed to smoking in the home are likely to have more severe asthma symptoms, more asthma-...
Article
How effective—and safe—are systemic steroids for acute low back pain?
- Author:
- Mark Johnson, DO
- Jon O. Neher, MD
- Leilani St. Anna, MLS, AHIP
EVIDENCE-BASED ANSWER: SHORT COURSES OF SYSTEMIC STEROIDS ARE LIKELY SAFE, but they are ineffective. A single dose of intramuscular (IM) or...
Article
When is the best time to clamp the umbilical cord after routine vaginal delivery?
- Author:
- Angela “Carmi” Hendrick, MD
- Jon O. Neher, MD
- Sarah M. Safranek, MLIS
EVIDENCE-BASED ANSWER: SOMETIME BETWEEN 30 SECONDS AND 2 MINUTES after delivery appears to be the best interval. In term infants, delayed clamping...
Article
What is the prognosis for patients with chronic urticaria?
- Author:
- Jennifer Engstrom, MD
- Jon O. Neher, MD
- Leilani St. Anna, MLIS, AHIP
EVIDENCE-BASED ANSWER: THE PROGNOSIS FOR CHRONIC URTICARIA IN PRIMARY CARE IS UNKNOWN; studies in dermatology clinics in multiple countries report...
Article
Do intra-articular steroid injections affect glycemic control in patients with diabetes?
- Author:
- Erin Kallock, MD
- Jon O. Neher, MD
- Leilani St. Anna, MLIS, AHIP
EVIDENCE-BASED ANSWER: YES, BUT THE CLINICAL IMPORTANCE IS MINIMAL. A single intra-articular steroid injection into the knee produces acute...
Article
What’s the best approach to diagnosing food allergies in infants?
- Author:
- Sara Benveniste, MD
- Jon O. Neher, MD
- Sarah Safranek, MLIS
EVIDENCE-BASED ANSWER: A WELL-DESIGNED ORAL FOOD CHALLENGE (OFC) is the most reliable diagnostic test for infants whose clinical history and...
Article
Do hyaluronic acid injections relieve OA knee pain?
- Author:
- Anirban Das, DO
- Jon O. Neher, MD
- Sarah Safranek, MLIS
EVIDENCE-BASED ANSWER: Yes, hyaluronic acid (HA) injections relieve pain more than placebo. The effect is small but similar to results from oral...
Article
Does reducing smoking in the home protect children from the effects of second-hand smoke?
- Author:
- Nathan R. Thompson, MD
- Jon O. Neher, MD
- Sarah Safranek, MLIS
EVIDENCE-BASED ANSWER: Yes, taking this step helps asthmatic children, and may even help nonasthmatic children. In families of asthmatic children...