Opinion
Is AFib ablation the fifth pillar in heart failure care? CASTLE-HTx
- Author:
- John M. Mandrola, MD
- Christian Sohns, MD, PhD
- And Philipp Sommer, MD
Catheter ablation was superior to medical therapy alone in terms a composite endpoint of death from any cause or left...
Opinion
The most important study from ESC: FRAIL-AF
- Author:
- John M. Mandrola, MD
This is the kind of science that medicine should celebrate. There were no soft endpoints, financial conflicts, or spin.
Opinion
Are fish oils on the hook for AFib risk?
- Author:
- John M. Mandrola, MD
Though there is plausibility and multiple reasons to infer causality of marine omega-3s in increasing AFib risk, the effect size remains unknown...
Opinion
Three surprising studies on exercise restriction and an exercise sweet spot
- Author:
- John M. Mandrola, MD
New data ‘do not support universal restriction of vigorous exercise in patients with’ hypertrophic cardiomyopathy.
News

Taking cardiac pacing from boring to super cool
- Author:
- John M. Mandrola, MD
Ablation has hogged the electrophysiology spotlight recently, but three presentations at the 2022 Heart Rhythm Society meeting put cardiac pacing...
Opinion

Why is vitamin D hype so impervious to evidence?
- Author:
- John M. Mandrola, MD
How many nonsignificant trials do we need before researchers stop studying vitamin D, doctors stop (routinely) measuring levels, and patients stop...
News

This doc still supports NP/PA-led care ... with caveats
- Author:
- John M. Mandrola, MD
We shouldn’t be worried about non-MD clinicians, said Dr. John Mandrola, but there are ways to increase confidence in NP and PA care.