Jennifer Smith is the editor of Oncology Practice, part of MDedge Hematology/Oncology. She was previously the editor of Hematology Times, an editor at Principal Investigators Association, and a reporter at The Oneida Daily Dispatch. She has a BS in journalism.
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Pregnancy deemed safe in BRCA-mutated breast cancer survivors
Pregnancy did not affect disease-free or overall survival, and complications were similar to the general population.
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Inhibitor produces high response rate in relapsed/refractory FL
CHICAGO – The PI3K-delta inhibitor ME-401, given with or without rituximab, produced an overall response rate of 80% in a phase 1b trial of...
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Olanzapine improves upon standard antiemetic therapy
CHICAGO – Complete response rates were higher among patients who received olanzapine plus standard therapy.
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Pembrolizumab improves 5-year OS in advanced NSCLC
CHICAGO – In a phase 1b trial of pembrolizumab, the 5-year OS rate was 23.2% in treatment-naive patients and 15.5% in previously treated patients...
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SC-PEG comparable to pegaspargase in young ALL/LL patients
CHICAGO – Patients who received SC-PEG had similar serum asparaginase activity, toxicities, and survival as patients...
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Combo produces ‘best response rate’ after first relapse in kids with AML
CHICAGO – CPX-351 followed by fludarabine, cytarabine, and filgrastim produced an overall response rate of 81%.
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Trial matches pediatric cancer patients to targeted therapies
Nearly a quarter of the patients screened as part of the National Cancer Institute–Children’s Oncology Group Pediatric MATCH trial have been...
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Entrectinib exhibits activity in children with solid tumors
Entrectinib produced responses in patients who had fusions or mutations in target genes.
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NCCN and MD Anderson award funding to researchers
Four researchers won funding via the NCCN Young Investigator Awards, and eight researchers will receive funding from the Andrew Sabin Family...
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NGS comparable to FC for minimal residual disease assessment
NEW ORLEANS – NGS of peripheral blood proved at least as effective as flow cytometry for assessing MRD in children and young adults with B-ALL who...
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Low-dose chemo feasible for older, frail patients with advanced gastroesophageal cancer
The lowest dose of oxaliplatin and capecitabine proved noninferior to two higher doses in a study of older and frail patients with advanced...
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Lenalidomide may reduce risk of progression from SMM to MM
At 3 years, the rate of progression-free survival was 91% in patients with smoldering multiple myeloma who were randomized to lenalidomide and 66...
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Diet linked to lower risk of death from breast cancer
A balanced, low-fat diet was associated with a 21% lower risk of death from breast cancer in a randomized study.
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QOL concerns prompt second-line therapy in children with ITP
NEW ORLEANS – Quality of life was the most common reason for starting second-line therapy in a cohort of children with immune thrombocytopenia.
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Master trial seeks to aid drug development for pediatric AML
NEW ORLEANS – “What we see in childhood AML is a lot different than what we see in adult AML, and this challenges the paradigm that we have...