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From failure to hope: Tracking the changing landscape of Alzheimer’s therapies
The Alzheimer's Drug Development Pipeline report, updated annually since 2016, classifies Alzheimer's therapies by their targets, their mechanisms...
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A new chapter for research on treating Huntington’s disease
BY JENNIE SMITH
The past decade has been a contradictory one for research on Huntington’s disease, marked by breakthroughs in the biology...
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AGA CPU stresses brain-gut aspects of bloating, distention and belching
The Clinical Practice Update helps untangle which tests are indicated and when for these common conditions.
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Hemostatic powder superior in controlling tumor bleeding
Standard endoscopic interventions resulted in lower rates of immediate hemostasis and more rebleeds.
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Crohn’s link seen for ultraprocessed foods
A meta-analysis of longitudinal cohort studies showed that people who consumed more ultraprocessed foods saw higher incidence of Crohn’s.
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Daily aspirin for stroke prevention in healthy elderly should be avoided
Data from a large randomized trial suggest that aspirin increases bleeding risk and is ineffective for primary stroke prevention in the elderly....
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Liver disease gets new name and diagnostic criteria
Formerly known as nonalcoholic fatty liver disease, the condition will now be known as metabolic dysfunction–associated steatotic liver disease (...
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In head and neck cancer, better outcomes seen in patients with overweight
Among 445 patients treated with chemoradiation, those with overweight saw improvements in survival and tumor recurrence, compared with patients...
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Medtronic to discontinue SmartPill capsule
A groundbreaking technology to pinpoint motility problems is being retired by its maker after 17 years on the market. Experts say there’s no easy...
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Race and ethnicity loom large in CRC screening
Disparities can be seen in everything from choice of test to bowel prep, according to a review.
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NAFLD increases risk for severe infections
Physicians should assess their patients’ vaccination status and seek to control modifiable risk factors, such as diabetes.
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Upadacitinib shows promise in treatment-resistant UC and Crohn’s
A real-world study from a single clinical practice saw fast responses and high rates of remission, including among people previously treated with...
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AGA update outlines best scenarios for EUS vascular interventions
Endoscopic ultrasound-guided interventions should be considered when the vascular target occurs in or near the gastrointestinal wall.
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Distal fecal washes reveal inflammation across ileac-colonic axis
A noninvasive method to locate inflammation, combined with sequencing, provided more robust information than biopsies
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New guideline weighs medication options for chronic constipation
Evidence for a range of prescription and over-the-counter therapies, along with specific recommendations for implementing them, are laid out in a...