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What are the risks of long-term PPI use for GERD symptoms in patients > 65 years?
EVIDENCE-BASED ANSWER: The use of proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) is significantly associated with...
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Should you switch the DAPT agent one month after ACS?
A randomized controlled trial says “Yes,” but current guidelines say “No.”
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Less is more when it comes to ketorolac for pain
It’s time to review our dosing with ketorolac for acute pain management.
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Time to Stop Glucosamine and Chondroitin for Knee OA?
The efficacy of chondroitin and glucosamine for knee osteoarthritis has been questioned for years. Now, the first pharmaceutically sponsored trial...
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Time to stop glucosamine and chondroitin for knee OA?
Prior studies provided conflicting results regarding the efficacy of these medications. This study offers evidence for discontinuing them.
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A New Protocol for RhD-negative Pregnant Women?
Can cell-free DNA testing reduce unnecessary use of anti-D immunoglobulin in RhD-negative women and still prevent harm to their RhD-positive...
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Does prophylactic azithromycin reduce the number of COPD exacerbations or hospitalizations?
EVIDENCE-BASED ANSWER: Yes for exacerbations, no for hospitalizations. Prophylactic azithromycin reduces the number of exacerbations by about 25...
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A new protocol for RhD-negative pregnant women?
Can cell-free DNA testing reduce unnecessary use of anti-D immunoglobulin in RhD-negative women and still prevent harm to their RhD-positive...
Article
Does exercise relieve vasomotor menopausal symptoms?
EVIDENCE-BASED ANSWER: No. Exercise doesn’t decrease the frequency or severity of vasomotor menopausal symptoms (VMS) in perimenopausal and...
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Tamsulosin for Patients With Ureteral Stones?
Recently, there has been debate about the effectiveness of tamsulosin for ureteral stone passage. The results of a new meta-analysis offer clarity...
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How do oral NSAIDs compare to other oral analgesics right after an acute musculoskeletal injury?
EVIDENCE-BASED ANSWER: Nonsteroidal anti-inflammatory drugs (NSAIDs) are at least as effective as other oral analgesics (opioids, acetaminophen)...
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Tamsulosin for patients with ureteral stones?
Yes, but only for some. Find out which of your patients can benefit.
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How do hyaluronic acid and corticosteroid injections compare for knee OA relief?
EVIDENCE-BASED ANSWER: Inconsistent evidence shows a small amount of pain relief early (one week to 3 months) with corticosteroid (CS) injections...
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Direct Oral Anticoagulants or Warfarin for A-fib?
For patients with atrial fibrillation, thromboembolism is a serious concern. But is warfarin or direct oral anticoagulation the better choice for...
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Direct oral anticoagulants or warfarin for A fib?
A recent study evaluated the effectiveness of 3 direct oral anticoagulants and warfarin in patients with atrial fibrillation. So which agents came...