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Novel schizophrenia drugs advance through pipeline
Three agents that address major unmet needs move to phase 3.
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Binge eating in ADHD may not be impulsivity-related
“Enhanced responsiveness to food cues may be a mediating mechanism underlying overeating in ADHD,” said Elizabeth Martin, MSc.
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Suicidality jumped in Israel during spring COVID-19 lockdown
The proportion of chats handled at the crisis hotline was 48% greater in the first half of 2020, compared with a year earlier.
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Nationwide study questions routine long-term beta-blocker post MI
Current guideline recommendations for long-term beta-blocker therapy after an acute MI may be outdated in the contemporary reperfusion era.
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Breathing enriched oxygen improves major depression
Dr. R. Haim Belmaker offers provocative results from a randomized, double-blind, controlled trial of a nonpharmacologic treatment.
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Liberalized European sports cardiology guidelines break new ground
The guidelines lift barriers to competitive sports participation by many with cardiovascular diseases.
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ECT reduces all-cause mortality in Danish study
“The take-home messages are that ECT does not lead to brain damage but rather to a profound gray matter increase,” said Dr. Alexander Sartorius....
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Watch for nonsuicidal self-injury in girls with ADHD, comorbidities
The significant risk factors for NSSI in patients with ADHD were affective disorders, suicidality, and psychotic disorders in both sexes.
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Novel calculator predicts cancer risk in patients with CVD
Individual lifetime total cancer risk ranges from 1% to 52%.
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Sleep EEG may predict later antidepressant response
“Being able to see if an antidepressant works within 1 week would be a real breakthrough,” said Catherine Harmer, DPhil.
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ISCHEMIA trial revisited: Some MAY benefit from invasive strategy
“This is an interesting hypothesis, for sure, that warrants further study to confirm whether it’s valid.” – Dr. Mark H. Drazner
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REALITY trial supports restrictive transfusion in anemic MI
Restrictive transfusion proves more effective and less costly than liberal transfusion.
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HOME-PE trial clarifies which pulmonary embolism patients to treat at home
“Who’s happy with the HOME-PE trial? I think everybody.” – Dr. Stavros V. Konstantinides
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RATE-AF trial boosts digoxin for rate control in permanent AFib
Study shows equally good rate control as with a beta-blocker, but with far fewer adverse events.
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Early rhythm control in AFib gains new life
EAST-AFNET 4 trial reanimates rhythm-control strategy as superior for 5-year cardiovascular outcomes.