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What is the clinical and economic return on taxpayers’ $260M investment in the WHI?
145,000 more quality-adjusted life years and at least $23.1 billion. According to sensitivity analysis, the 95% confidence interval for the net...
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Hemorrhagic ovarian cysts: One entity with many appearances
Interpretation of 12 stunning images, including color Doppler, demonstrating tell-tale signs of, as well as findings not to be confused with, this...
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When should a menopausal woman discontinue hormone therapy?
Although this question is common in clinical practice, the answer isn’t clear-cut
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Is one oral estrogen formulation safer than another for menopausal women?
YES. Women using estradiol had a lower risk of incident venous thromboembolism than women using conjugated equine estrogens (CEE), according to...
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Best age to begin screening mammograms: How I manage my patients
I support individual preferences regarding screening for average-risk women in their 40s
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In young hysterectomized women, does unopposed estrogen therapy increase overall survival?
Yes. Between 2002 and 2011, a minimum of 18,601 and as many as 91,610 excess deaths occurred among hysterectomized US women aged 50 to 59 years,...
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Is there a link between impaired mobility and urinary incontinence in elderly, community-dwelling women?
Yes. In this population, impaired mobility is associated with urge but not stress incontinence, according to an observational, cross-sectional...
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Do cosmetic breast implants hinder the detection of malignancy and reduce breast cancer–specific survival?
Yes. According to this systematic review and two meta-analyses of observational studies, cosmetic breast augmentation adversely affects survival...
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UPDATE ON MENOPAUSE
Our understanding deepens of the benefits and risks of hormone therapy in different formulations and populations
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New treatment option for vulvar and vaginal atrophy
Ospemifene has been found to reduce pain with sexual intercourse and increase vaginal mucosal maturation and pH
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Tips on counseling women about mammography screening
How does Dr. Kaunitz counsel women of different age groups and risk categories?
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Are hospital claims about the robotic approach to gynecologic surgery based on reliable data—or mostly hype?
Many claims reflect marketing rather than data, according to this analysis of content from hospital Web sites. Not only was little content based...
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Does treatment of cervical intraepithelial neoplasia always increase the risk of preterm birth in subsequent gestations?
No. In this retrospective-prospective cohort study from England, the risk of preterm delivery in women treated for cervical intraepithelial...